| IED ID | IndEnz0002014573 |
| Enzyme Type ID | protease014573 |
| Protein Name |
Probable metalloprotease ARX1 EC 3.-.-.- Associated with ribosomal export complex protein 1 |
| Gene Name | ARX1 KLLA0F11979g |
| Organism | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Kluyveromyces Kluyveromyces lactis (Yeast) (Candida sphaerica) Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
| Enzyme Sequence | MALQISKEDTQVLLKDKNVLIEPTIEKYRTAGQIAQTALNFLISLINKMYHEKSMEPLPIHQLCLLTDSFIADCLSTKFNNKVNEKGISMPTCIDIDEINENWCPEVDDIENLSRWNQKSRSTKSIELCNGVTSSLSGFLKVGDVAKITLGCHIDGYTCNVSHTVVIYPTVQDAQSGKLLPEAALLGGKADALAATHIAVESVTNLLAAANDLTKLPADFNATKVTGSLIRTVVDTIAQSYNCCVVPGSRIRRIKRFLSGQNENIIVERDFKGVIWTESHQEAAMLARTVNETAVDVKRKNPFITEDTVVPTDDFTVVKGEVYMIDLKLAPLQGLEPGLITLHTVDQFSGKSESSDVVARPGAICRDFSKSHVLKLRAARQVLTRLDKQGVYPTKLAHIADSFPLDVQEPDFETIKQEIKPFRLGLSEISNNYLTIDRDVTIVKHVPWAKILDLTNPSGVSSYDAMAKNKGLYPGFELPLPKLGLSNLQLKSLLKKHSTPVPVVRQCVTVAICDEELLRISGNLKSNWVHSVYSMDTASNIVAGIFKLAQLSEDKRFGLKIRETQPWKMKF |
| Enzyme Length | 571 |
| Uniprot Accession Number | Q6CKB6 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.-.-.- |
| Enzyme Function | FUNCTION: Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1) |
| Keywords | Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Nucleus;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 63,261 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |