| IED ID | IndEnz0002014617 |
| Enzyme Type ID | protease014617 |
| Protein Name |
Cysteine proteinase 6 EC 3.4.22.- |
| Gene Name | cprF CP6 DDB_G0279185 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MKVLSALCVLLVSVATAKQQLSELQYRNAFTNWMIAHQRHYSSEEFNGRFNIFKANMDYINEWNTKGSETVLGLNVFADITNEEYRATYLGTPFDASSLEMTPSEKVFGGVQANSVDWRAKGAVTPIKNQGECGGCWSFSATGATEGAQYIANGDSDLTSVSEQQLIDCSGSYGNNGCEGGLMTLAFEYIINNGGIDTESSYPFTANTEKCKYNPSNIGAELSSYVNVTSGSESDLAAKVTQGPTSVAIDASQPSFQFYSSGIYNEPACSSTQLDHGVLAVGFGSGSSGSQSQSAGSQSQSSNNNWSESSQSQDSNSWSQSSQSQSSQDSNSWSQSSQSQGSNSFTGAGTGSGSGSVSGSGSASGSSSFSGSSNGGNSNSGDYPTDGNYWIVKNSWGLDWGINGYILMSKDKDNQCGIATMASIPQAIPKSKWN |
| Enzyme Length | 434 |
| Uniprot Accession Number | Q94503 |
| Absorption | |
| Active Site | ACT_SITE 136; /evidence=ECO:0000250; ACT_SITE 276; /evidence=ECO:0000250; ACT_SITE 394; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Glycosylation (2); Propeptide (1); Region (1); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Lysosome;Phosphoprotein;Protease;Reference proteome;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Lysosome {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11553701; 16257986; 22120990; |
| Motif | |
| Gene Encoded By | |
| Mass | 45,765 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |