Detail Information for IndEnz0002014873
IED ID IndEnz0002014873
Enzyme Type ID protease014873
Protein Name Protease HtpX homolog 1
EC 3.4.24.-
Gene Name htpX1 MM_1236
Organism Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Taxonomic Lineage cellular organisms Archaea Euryarchaeota Stenosarchaea group Methanomicrobia Methanosarcinales Methanosarcinaceae Methanosarcina Methanosarcina mazei (Methanosarcina frisia) Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
Enzyme Sequence MKNMLKTTVLLAALTGLLVIIGDYFGGTGGMIIAFLFAVVLNFGSYWYSDKIVLKMYRAKEVSPAEAPNLHRIVDGLVMKAGIPKPKVYIVQSGMPNAFATGRDPKHAAVAATTGILELLSYEEMEGVLAHELAHVKNRDTLISAIAATLAGVVTMLAHWAQWAAIFGGFGGRDDDGNGGIVGLIAMAIVAPIAATLIQLAISRSREFAADEEGARISRKPWALADALEKLEYGNSHYRARVSDVQAKESSAHMFIVNPLKGGAVQSLFRTHPVTDERVRRLRAMKF
Enzyme Length 287
Uniprot Accession Number Q8PXI2
Absorption
Active Site ACT_SITE 132; /evidence=ECO:0000255|HAMAP-Rule:MF_00188
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (3); Transmembrane (4)
Keywords Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00188}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00188}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 31,005
Kinetics
Metal Binding METAL 131; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 135; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 207; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188
Rhea ID
Cross Reference Brenda