| IED ID | IndEnz0002015133 |
| Enzyme Type ID | protease015133 |
| Protein Name |
Heat shock 70 kDa protein 3 AtHsp70-3 Heat shock protein 70-3 Heat shock cognate 70 kDa protein 3 AtHsc70-3 Heat shock cognate protein 70-3 |
| Gene Name | HSP70-3 HSC70-3 HSC70-G7 At3g09440 F11F8 F3L24.33 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPINTVFDAKRLIGRRFTDSSVQSDIKLWPFTLKSGPAEKPMIVVNYKGEDKEFSAEEISSMILIKMREIAEAYLGTTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRALRRLRTACERAKRTLSSTAQTTIEIDSLFDGIDFYAPITRARFEELNIDLFRKCMEPVEKCLRDAKMDKNSIDDVVLVGGSTRIPKVQQLLVDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIQRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMVQEAEKYKSEDEEHKKKVDAKNALENYAYNMRNTIRDEKIGEKLAGDDKKKIEDSIEAAIEWLEANQLAECDEFEDKMKELESICNPIIAKMYQGGEAGGPAAGGMDEDVPPSAGGAGPKIEEVD |
| Enzyme Length | 649 |
| Uniprot Accession Number | O65719 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions. {ECO:0000305}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Region (1); Sequence conflict (2) |
| Keywords | ATP-binding;Chaperone;Cytoplasm;Nucleotide-binding;Nucleus;Reference proteome;Stress response |
| Interact With | |
| Induction | INDUCTION: By heat shock and by cold. Up-regulated by virus infection. {ECO:0000269|PubMed:11402207, ECO:0000269|PubMed:15805473}. |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305|PubMed:14505352}. Nucleus matrix {ECO:0000269|PubMed:14505352}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11782485; 12427978; 12671088; 12753585; 14760709; 15247402; 15273295; 15356332; 15489280; 15489341; 15494554; 15821981; 15908592; 16061506; 16247729; 16254930; 16287169; 16502469; 16547123; 16621846; 16679420; 16972165; 17059406; 17151019; 17317660; 17360592; 17404219; 17644812; 18156220; 18184068; 18189342; 18222516; 18305208; 18431481; 18538804; 18633119; 18650403; 18684336; 18775970; 18783601; 18784283; 18790826; 20351290; 20687615; 20736450; 23148892; 24556609; 28627464; 30833711; 32344669; 33506954; |
| Motif | |
| Gene Encoded By | |
| Mass | 71,148 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |