IED ID | IndEnz0002015284 |
Enzyme Type ID | protease015284 |
Protein Name |
Bromelain inhibitor BI Bromein Cleaved into: Bromelain inhibitor 1 chain B BI-I B Bromelain inhibitor VII light chain BI-VII L ; Bromelain inhibitor 1 chain A BI-I A Bromelain inhibitor VII heavy chain BI-VII H ; Bromelain inhibitor 3 chain B BI-III B ; Bromelain inhibitor 3 chain A BI-III A ; Bromelain inhibitor 2 chain B BI-II B Bromelain inhibitor VI light chain BI-VI L ; Bromelain inhibitor 2 chain A BI-II A Bromelain inhibitor VI heavy chain BI-VI H |
Gene Name | |
Organism | Ananas comosus (Pineapple) (Ananas ananas) |
Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Bromeliaceae Bromelioideae Ananas Ananas comosus (Pineapple) (Ananas ananas) |
Enzyme Sequence | MNMLLLFLHEVINGERVTLTACSECVCPLQTSSSDDEYKCYCADTYSDCPGFCKKCKAEFGKYICLDLISPNDCVKPVSSSEAKQKMIKGERVTLTACSECVCPLRTSSSDEEYKCYCTDTYSDCPGFCKKCKAEFGKYICLDLISPNDCVKPVSSLEAKQNMIKEERVTLTACSECVCPLRTSSSDEEYKCYCTDTYSDCPGFCKTCKAEFGKYICLDLISPNDCVKPVSSWEARQKIKLLQGRE |
Enzyme Length | 246 |
Uniprot Accession Number | P01068 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Weak inhibitor of cysteine proteinases. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Beta strand (4); Disulfide bond (15); Natural variant (1); Peptide (6); Propeptide (6); Signal peptide (1) |
Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Protease inhibitor;Repeat;Signal |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000269|PubMed:1112827 |
Structure 3D | NMR spectroscopy (2) |
Cross Reference PDB | 1BI6; 2BI6; |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 27,521 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |