Detail Information for IndEnz0002015284
IED ID IndEnz0002015284
Enzyme Type ID protease015284
Protein Name Bromelain inhibitor
BI
Bromein

Cleaved into: Bromelain inhibitor 1 chain B
BI-I B
Bromelain inhibitor VII light chain
BI-VII L
; Bromelain inhibitor 1 chain A
BI-I A
Bromelain inhibitor VII heavy chain
BI-VII H
; Bromelain inhibitor 3 chain B
BI-III B
; Bromelain inhibitor 3 chain A
BI-III A
; Bromelain inhibitor 2 chain B
BI-II B
Bromelain inhibitor VI light chain
BI-VI L
; Bromelain inhibitor 2 chain A
BI-II A
Bromelain inhibitor VI heavy chain
BI-VI H
Gene Name
Organism Ananas comosus (Pineapple) (Ananas ananas)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Bromeliaceae Bromelioideae Ananas Ananas comosus (Pineapple) (Ananas ananas)
Enzyme Sequence MNMLLLFLHEVINGERVTLTACSECVCPLQTSSSDDEYKCYCADTYSDCPGFCKKCKAEFGKYICLDLISPNDCVKPVSSSEAKQKMIKGERVTLTACSECVCPLRTSSSDEEYKCYCTDTYSDCPGFCKKCKAEFGKYICLDLISPNDCVKPVSSLEAKQNMIKEERVTLTACSECVCPLRTSSSDEEYKCYCTDTYSDCPGFCKTCKAEFGKYICLDLISPNDCVKPVSSWEARQKIKLLQGRE
Enzyme Length 246
Uniprot Accession Number P01068
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Weak inhibitor of cysteine proteinases.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (4); Disulfide bond (15); Natural variant (1); Peptide (6); Propeptide (6); Signal peptide (1)
Keywords 3D-structure;Direct protein sequencing;Disulfide bond;Protease inhibitor;Repeat;Signal
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..19; /evidence=ECO:0000269|PubMed:1112827
Structure 3D NMR spectroscopy (2)
Cross Reference PDB 1BI6; 2BI6;
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 27,521
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda