Detail Information for IndEnz0002015318
IED ID IndEnz0002015318
Enzyme Type ID protease015318
Protein Name Chymotrypsin inhibitor WCI
Chloroform/methanol-soluble protein WCI
Gene Name
Organism Triticum aestivum (Wheat)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Pooideae Triticodae Triticeae Triticinae Triticum Triticum aestivum (Wheat)
Enzyme Sequence TSIYTCYEGVGLPVDPLQGCHYYVTSQTCGFVPLLPIEVMKDRCCRELAAISSNCRCEGLRVFIDRAFPPSQSQGGGPPQPPLAPRCPTEVKRDFARTLALPGQCNLPTIHGGPYCVFP
Enzyme Length 119
Uniprot Accession Number P83207
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibits bovine, insect and wheat chymotrypsins. Inhibits bovine chymotrypsin with Ki of 0.6 nM. Does not inhibit human or wheat alpha-amylases, bovine pancreatic trypsin, or trypsin-like activity isolated from wheat. {ECO:0000269|PubMed:21617989}.
Temperature Dependency BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 25 degrees Celsius. {ECO:0000269|PubMed:21617989};
PH Dependency BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH range is 7.0-9.0. {ECO:0000269|PubMed:21617989};
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (5); Natural variant (1)
Keywords Direct protein sequencing;Disulfide bond;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P01087}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 12,944
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda