| IED ID | IndEnz0002015376 |
| Enzyme Type ID | protease015376 |
| Protein Name |
Leukocyte elastase inhibitor Serpin B1 |
| Gene Name | serpinb1 |
| Organism | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amphibia Batrachia Anura Pipoidea Pipidae Xenopodinae Xenopus Silurana Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
| Enzyme Sequence | MENLSSACTHFSFDLFRKINENNATGNVFFSPISISTALAMVLLGARGNTAQQISRILHFDAVKDLHSNFQTLNAEINKKNVSSYALNLANRLFGEKSFKFLPDFLSSVKKQYNADLGTVDFISAAEDARKEINTWVSEQTKGKIPEVLSAGAVNSFTKLVLVNAIYFKGDWAKKFKAEHTKDMPFQLNKKEQKTVKMMYQMEKLPFNYIPEINCRVLELPYVDYELSMVIVLPDNINDDTTGLQQLEKELSLEKINEWTENMMPIDVHVHLPKFKLEDSYKLKSQLAGMGMADLFEAGSADLSGMSGSNDLYLSEVIHKSFVEVNEEGTEAAAASAGIAMMCLMREEEFNANHPFLFFIRHNATKSILFFGRYSSP |
| Enzyme Length | 377 |
| Uniprot Accession Number | Q5I0S8 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Regulates the activity of the neutrophil proteases. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Modified residue (1); Site (1) |
| Keywords | Acetylation;Cytoplasm;Protease inhibitor;Reference proteome;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | MOD_RES 1; /note=N-acetylmethionine; /evidence=ECO:0000250 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 42,519 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |