| IED ID | IndEnz0002015379 |
| Enzyme Type ID | protease015379 |
| Protein Name |
Mitochondrial inner membrane protease atp23 EC 3.4.24.- |
| Gene Name | atp23 AFUA_2G07560 |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Enzyme Sequence | MSDSQPCSTPSTRGKSDSGYIPGDDTWTQWRNIFAILTGQMTDEGKEQFRIARDIRNEAADCKRCEDQRDYLLQYSPIIRFLSDNIRQLRGDLSSHNIYCRRCTSRKAGGFDPEYGILLCANEMKDQGHLEDTMAHEMVHAYDHLRFKVDWTDNLRHAACTEIRASSLSGECRWAREFFRRGQWKFTQQHQECVRRRAILSVRARPGCKDEAHAEKVVNEVWDSCFRDTRPFDEIYR |
| Enzyme Length | 237 |
| Uniprot Accession Number | Q4X261 |
| Absorption | |
| Active Site | ACT_SITE 137; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (1); Erroneous gene model prediction (1); Metal binding (2); Region (1) |
| Keywords | Hydrolase;Membrane;Metal-binding;Metalloprotease;Mitochondrion;Mitochondrion inner membrane;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane. {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 27,784 |
| Kinetics | |
| Metal Binding | METAL 136; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250; METAL 140; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |