| IED ID | IndEnz0002015380 |
| Enzyme Type ID | protease015380 |
| Protein Name |
Mitochondrial inner membrane protease atp23 EC 3.4.24.- |
| Gene Name | atp23 AN5816 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MPNSQTSNSQPQVSEKDVDTGFRKGDDTFTHWRNVFNILTGRMTDEGIEQFRVARDLRNEAADCKRCEDQRDYLLQWSPIIRYMSDSIRQLGGDLSSHNIYCRRCTNRKAGGFDPEYGILICANEMKDQGHLEDTMAHEMVHAYDHLRFKVDWTNNLRHAACTEIRASSLSGECRWAREFFRRGQWKLTQQHQECVRRRAVLSVMARPGCQDKGHAEKVVNEVWDSCFRDTRPFDEIFR |
| Enzyme Length | 239 |
| Uniprot Accession Number | Q5B0W4 |
| Absorption | |
| Active Site | ACT_SITE 139; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (1); Metal binding (2); Region (1) |
| Keywords | Hydrolase;Membrane;Metal-binding;Metalloprotease;Mitochondrion;Mitochondrion inner membrane;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane. {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 28,014 |
| Kinetics | |
| Metal Binding | METAL 138; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250; METAL 142; /note=Divalent metal cation; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |