| IED ID | IndEnz0002015554 |
| Enzyme Type ID | protease015554 |
| Protein Name |
Protease inhibitor 2 CmPI-II Protease inhibitor-II |
| Gene Name | |
| Organism | Cenchritis muricatus (Beaded periwinkle) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Littorinimorpha Littorinoidea Littorinidae Cenchritis Cenchritis muricatus (Beaded periwinkle) |
| Enzyme Sequence | AEDCVGRKACTREWYPVCGSDGVTYSNPCNFSAQQEQCDPNITIAHMGEC |
| Enzyme Length | 50 |
| Uniprot Accession Number | P84755 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Serine protease inhibitor. Strongly inhibits human neutrophil elastase and trypsin, also inhibits porcine pancreatic elastase and subtilisin A. Does not inhibit chymotrypsin, plasma kallikrein, pancreatic kallikrein, thrombin or papain. {ECO:0000269|PubMed:16546427, ECO:0000269|PubMed:17976011}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (3); Chain (1); Disulfide bond (2); Domain (1); Glycosylation (2); Helix (1); Site (1); Turn (1) |
| Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Glycoprotein;Protease inhibitor;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | NMR spectroscopy (1) |
| Cross Reference PDB | 2N71; |
| Mapped Pubmed ID | 30930219; |
| Motif | |
| Gene Encoded By | |
| Mass | 5,486 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |