| IED ID |
IndEnz0002015652 |
| Enzyme Type ID |
protease015652 |
| Protein Name |
Transcriptional activator NprA
|
| Gene Name |
nprA |
| Organism |
Geobacillus stearothermophilus (Bacillus stearothermophilus) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Firmicutes
Bacilli
Bacillales
Bacillaceae
Geobacillus
Geobacillus stearothermophilus (Bacillus stearothermophilus)
|
| Enzyme Sequence |
MADGIISVSYLSKIENNQVVPSEEVLRLLCQRLGINNILKNRQDELTSKLLLWYKTITDKNRQEAARMYEEIKRTFDDVQGAESIAYFLLFEMRYHLLLKDIHTVEALLIKLRELYDTFDDVMKYYYYKFLGLLYYCKEKYEDALEYYKKAEQRFRSQSFEKWEEADLHYLLALVYSRLWRILGCINYAQHALAIYQSEYDLKRSAECHILLGICYRRYGEVDQAIECYSLAHKIAQIINDTELLGTIEHNLGYLMSMKHEHYEAIQHYKKSLLYKRNSSLQARFITLFSLIKEYYVSKNYKKALANVEESLQLLKREKDGMTTYYEYYLHFTVYQYLLSEDISENEFETFMKDRVLPYFQRFKKYEDVAQYAEYLAIYYEKRHKYKLASKFYKMSYQFLKNMINI |
| Enzyme Length |
406 |
| Uniprot Accession Number |
P43130 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Activates the transcription of nprS by about five fold. May bind to the upstream region of nprS promoter. {ECO:0000269|PubMed:2203733}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Repeat (4) |
| Keywords |
Activator;DNA-binding;Repeat;TPR repeat;Transcription;Transcription regulation |
| Interact With |
|
| Induction |
INDUCTION: Expressed in the late logarithmic growth phase. {ECO:0000269|PubMed:2203733}. |
| Subcellular Location |
|
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
49,154 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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