Detail Information for IndEnz0002015898
IED ID IndEnz0002015898
Enzyme Type ID protease015898
Protein Name High frequency lysogenization protein HflD
Gene Name hflD E2348C_1273
Organism Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli Escherichia coli O127:H6 Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Enzyme Sequence MAKNYYDITLALAGICQSARLVQQLAHQGHCDGDALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
Enzyme Length 213
Uniprot Accession Number B7UQ41
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Negative regulator of phage lambda lysogenization. Contributes to the degradation of the phage regulatory protein CII. Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease. {ECO:0000255|HAMAP-Rule:MF_00695}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Coiled coil (1)
Keywords Cell inner membrane;Cell membrane;Coiled coil;Cytoplasm;Membrane
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm. Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00695}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_00695}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_00695}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 22,934
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda