| IED ID | IndEnz0002015921 |
| Enzyme Type ID | protease015921 |
| Protein Name |
Protease HtpX homolog EC 3.4.24.- |
| Gene Name | htpX PF1135 |
| Organism | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
| Taxonomic Lineage | cellular organisms Archaea Euryarchaeota Thermococci Thermococcales Thermococcaceae Pyrococcus Pyrococcus furiosus Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
| Enzyme Sequence | MGIGLWVRTGLLMAFLTGLLVGIGYLIGGQGGMIIAFTIALFMNFFSYWFSDSIVLSWYNARIVSEEEAPELHRIVEKLAMQAGIPKPRVAIVPTLVPNAFATGRSPEHAVVAVTEGLLRILNRDELEGVIAHEISHIKNRDTLIQTIAAVLAGAIMVLVNFARWSLWFGAYDEDRDGGNIVALILAIILAPIAATLIQLAISRSREYLADETGAKISGKPHALASALMKIEEAVRYRPLKNGNPATAHMFIVNPFRGVDFVELFSTHPPTEKRIERLRKIAMEMGIIF |
| Enzyme Length | 289 |
| Uniprot Accession Number | Q8U1S0 |
| Absorption | |
| Active Site | ACT_SITE 134; /evidence=ECO:0000255|HAMAP-Rule:MF_00188 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Metal binding (3); Transmembrane (4) |
| Keywords | Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00188}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00188}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 31,802 |
| Kinetics | |
| Metal Binding | METAL 133; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 137; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 207; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188 |
| Rhea ID | |
| Cross Reference Brenda |