Detail Information for IndEnz0002015953
IED ID IndEnz0002015953
Enzyme Type ID protease015953
Protein Name Cysteine proteinase A
EC 3.4.22.-
Gene Name LMCPA
Organism Leishmania mexicana
Taxonomic Lineage cellular organisms Eukaryota Discoba Euglenozoa Kinetoplastea (kinetoplasts) Metakinetoplastina Trypanosomatida Trypanosomatidae Leishmaniinae Leishmania Leishmania Leishmania mexicana species complex Leishmania mexicana
Enzyme Sequence MARRNPLLFAIVVTILFVVCYGSALIAQTPPPVDNFVASAHYGSFKKRHGKAFGGDAEEGHRFNAFKQNMQTAYFLNTQNPHAHYDVSGKFADLTPQEFAKLYLNPDYYARHLKNHKEDVHVDDSAPSGVMSVDWRDKGAVTPVKNQGLCGSCWAFSAIGNIEGQWAASGHSLVSLSEQMLVSCDNIDEGCNGGLMDQAMNWIMQSHNGSVFTEASYPYTSGGGTRPPCHDEGEVGAKITGFLSLPHDEERIAEWVEKRGPVAVAVDATTWQLYFGGVVSLCLAWSLNHGVLIVGFNKNAKPPYWIVKNSWGSSWGEKGYIRLAMGSNQCMLKNYPVSATVESPHTPHVPTTTA
Enzyme Length 354
Uniprot Accession Number P25775
Absorption
Active Site ACT_SITE 153; /evidence=ECO:0000250; ACT_SITE 289; /evidence=ECO:0000250; ACT_SITE 309; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Disulfide bond (3); Glycosylation (1); Propeptide (1); Signal peptide (1)
Keywords Disulfide bond;Glycoprotein;Hydrolase;Protease;Signal;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..24; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 38,745
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda