| IED ID | IndEnz0002015969 |
| Enzyme Type ID | protease015969 |
| Protein Name |
Extracellular metalloprotease NCU07200 EC 3.4.24.- |
| Gene Name | B8G12.220 NCU07200 |
| Organism | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora Neurospora crassa Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
| Enzyme Sequence | MQIKSFLLAAAAAPAALGAAVNTIKPFNCGTDAPSRQHIQMTKELAEKEAAMAAEGIMTAQATINVNVYFHVVAASTALSDGYVTSTMINNQVATLNKAYAPHNIQFTLKGTDYTINSNWAVDGSELAMKKALRKGTYKDLNLYILKDLGDALGYCYFPTSVTSKSNDWYYDGCSILYDTLPGGSLTNYNLGHTSTHEIGHWFGLYHTFQGGCSGNGDYVSDTPAQASASSGCPTGRDSCPSQPGLDPIHNYMDYSYDTCYEEFTSGQRTRMTSYWNQYRANASV |
| Enzyme Length | 285 |
| Uniprot Accession Number | Q871C5 |
| Absorption | |
| Active Site | ACT_SITE 198; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Secreted metalloproteinase that allows assimilation of proteinaceous substrates. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Disulfide bond (1); Glycosylation (1); Metal binding (2); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Secreted;Signal;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 30,970 |
| Kinetics | |
| Metal Binding | METAL 197; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 201; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID | |
| Cross Reference Brenda |