| IED ID | IndEnz0002015986 |
| Enzyme Type ID | protease015986 |
| Protein Name |
Collagenolytic protease EC 3.4.21.32 CSC Fragment |
| Gene Name | |
| Organism | Carcinus maenas (Common shore crab) (Green crab) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Pleocyemata Brachyura (short-tailed crabs) Eubrachyura Heterotremata Portunoidea Carcinidae Carcinus Carcinus maenas (Common shore crab) (Green crab) |
| Enzyme Sequence | IVGGMEATPHSWPHQVA |
| Enzyme Length | 17 |
| Uniprot Accession Number | P81609 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of proteins, with broad specificity for peptide bonds. Native collagen is cleaved about 75% of the length of the molecule from the N-terminus. Low activity on small molecule substrates of both trypsin and chymotrypsin.; EC=3.4.21.32; |
| DNA Binding | |
| EC Number | 3.4.21.32 |
| Enzyme Function | FUNCTION: Serine protease with chymotryptic, collagenolytic and SANA activities. {ECO:0000269|PubMed:8896334}. |
| Temperature Dependency | BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 30 degrees Celsius.; |
| PH Dependency | BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is 7-8.; |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (1); Non-terminal residue (1) |
| Keywords | Collagen degradation;Direct protein sequencing;Hydrolase;Protease;Secreted;Serine protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 1,817 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |