Detail Information for IndEnz0002016077
IED ID IndEnz0002016077
Enzyme Type ID protease016077
Protein Name Probable leucine aminopeptidase ARB_03492
EC 3.4.11.-
Leucyl aminopeptidase ARB_03492
Gene Name ARB_03492
Organism Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)
Enzyme Sequence MKVSAIAAVAALAAVAVAGPVRPSGDKYLIELGPGKTQWVTKDQKHKMRAAGQTFIDITNEIGTNFVATKPVAANYPKNIAHPSMVSSMIANLSKENLMRDLQAMSEFNNRYYESQTGVESANWLMEQVKKVIDESGAQGAKVEKIENQFNQFNIIATIPGSSESTVIVGAHQDSINQEDPMGGRAPGADDNGSGSVVVLEALRGVLGSKAFRAANNTNTLEFHWYAGEEGGLLGSQTVFSKYKSDGRQVKAMLNQDLAGFKGQGQEQFGLITDNTNQELNQFCKMIVEKYASIPIVDTECGYACSDHASADRNGFPASMVAETAFEDSNPHIHSADDTVEYLDFDHMLEHAKVALGFMTELGMASNL
Enzyme Length 368
Uniprot Accession Number D4B4V2
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.11.-
Enzyme Function FUNCTION: Probable extracellular aminopeptidase which contributes to pathogenicity. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (1); Glycosylation (3); Metal binding (6); Signal peptide (1)
Keywords Aminopeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Signal;Virulence;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 39,741
Kinetics
Metal Binding METAL 172; /note=Zinc 1; /evidence=ECO:0000250; METAL 191; /note=Zinc 1; /evidence=ECO:0000250; METAL 191; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 230; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 257; /note=Zinc 1; /evidence=ECO:0000250; METAL 334; /note=Zinc 2; catalytic; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda