| IED ID | IndEnz0002016088 |
| Enzyme Type ID | protease016088 |
| Protein Name |
Metacaspase-1 EC 3.4.22.- PfMC1 Cleaved into: Large subunit p20; Small subunit p10 |
| Gene Name | MCA1 PBANKA_1131400 |
| Organism | Plasmodium berghei (strain Anka) |
| Taxonomic Lineage | cellular organisms Eukaryota Sar Alveolata Apicomplexa Aconoidasida Haemosporida (haemosporidians) Plasmodiidae Plasmodium Plasmodium (Vinckeia) Plasmodium berghei Plasmodium berghei (strain Anka) |
| Enzyme Sequence | MSLQMDKIYVKVHELKFVNNLERNSHYVKIYWDDKKYKSQTKDGGCYIFNETFLIPITNIYDQKDQIIYVEIWESNLLNKQCAYTFFTLNSIKIGQIIKENITFIEVLKKCTLGLSINIVRNQKDILFFNIKELLPTFQDQEIINAVWKNEDEASIIKQLINLNTIDGITNIGNYKNSQNYNETLQKPKENISIYKSGEEIENSYIPSSTPEYVSHYIYKGAGENSSNYINKTKDTLFPTYLNNYAYNNNIKNVYDTPNGAHYSSNNNSGSNNAYSNFDHNINNSPKNNVPFSNSDNDKIFHYSRNYMPSPNSEKMLYFSCGNKKKALLIGIDYCGTQNELKGSINDAIITNELLIKKYNFYDSSMNILKLIDNQTNPNYRPTKRNILSALEWLVQDNNPGDIFFFFYSGHSYKKYDYTCIEKGGYNQTIVPCDFKTEGEIIDNDLHKYLIQPLKDGVKLVSFIDCPNSEGILNLGYKYKLKKEKWKETYNPFHVLADVTQFSYSKINEFPTEINLLEHVLITNNIEALTYHYMIQSIHSYINLYNKKKKKKIFLMSSQKFNIDRKFDFNHILKNSNSELGQQKNIIKWKKNKKK |
| Enzyme Length | 595 |
| Uniprot Accession Number | A0A509APC7 |
| Absorption | |
| Active Site | ACT_SITE 411; /evidence=ECO:0000250|UniProtKB:Q08601; ACT_SITE 466; /evidence=ECO:0000250|UniProtKB:Q08601 |
| Activity Regulation | ACTIVITY REGULATION: Activated by Ca(2+). {ECO:0000250|UniProtKB:Q8IDF3}. |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Cysteine protease that cleaves specifically after arginine or lysine residues. {ECO:0000250|UniProtKB:Q8IDF3}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (3); Propeptide (1) |
| Keywords | Hydrolase;Protease;Reference proteome;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 69,604 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |