Detail Information for IndEnz0002016211
IED ID IndEnz0002016211
Enzyme Type ID protease016211
Protein Name Probable signal peptidase I-2
SPase I-2
EC 3.4.21.89
Leader peptidase I-2
Gene Name lepB2 slr1377
Organism Synechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Cyanobacteria/Melainabacteria group Cyanobacteria Synechococcales Merismopediaceae Synechocystis unclassified Synechocystis Synechocystis sp. PCC 6803 Synechocystis sp. (strain PCC 6803 / Kazusa)
Enzyme Sequence MTENIVRETSKKKESPPENTWLELGKTMVTAVILAIGIRTFVAEARYIPSSSMEPTLQINDRLIIEKISYRLRDPERGEIVVFNPTDALKAKNFHDAFIKRIIGLPGDEVRVSQGNVYVNGKMLDENYIAAPPAYEYGPVKVPDDQYLVLGDNRNNSYDSHYWGFVPREKLLGRAFVRFWPVPRVGLLTDDAEREAVEISPQAWESPAISPQTVPESR
Enzyme Length 218
Uniprot Accession Number P73157
Absorption
Active Site ACT_SITE 52; /evidence=ECO:0000250; ACT_SITE 100; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.; EC=3.4.21.89;
DNA Binding
EC Number 3.4.21.89
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Topological domain (2); Transmembrane (1)
Keywords Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 24,733
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda