Detail Information for IndEnz0002016218
IED ID IndEnz0002016218
Enzyme Type ID protease016218
Protein Name Probable leucine aminopeptidase MCYG_03459
EC 3.4.11.-
Leucyl aminopeptidase MCYG_03459
Gene Name MCYG_03459
Organism Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Microsporum Arthroderma otae (Microsporum canis) Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Enzyme Sequence MKISTLAVVSAFAVTAIAGPVRPDGIGSDKYLIELGPGETQWVTKDQKHHMRAAGKTFIDITDEFGSGFTTTEVVPANYPKSARHASLIKPLIANLSKENLMRDLTTLTKFNNRYYESDTGVESATWILQQVQKIIKDSGVKGAKVEKFTNQFKQFNIIATIPGSSKSTVIVGAHQDSINSKSPMKGRAPGADDNGSGTVVILEAFRNILKSKAIQAANATNTLEFHWYAGEEGGLLGSNNIFKKYKADGRQVKAMLNQDLTGFTNNGKPEQLGLIADNTNQQLNEFCKMIVKQYASIPIVEAKCGYACSDHASAHRNGFPASFVAETSYRNTNPYLHTDGDVIANLNFNHMLEHAKVVLGFMGELAMAPNL
Enzyme Length 372
Uniprot Accession Number C5FLR8
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.11.-
Enzyme Function FUNCTION: Probable extracellular aminopeptidase which contributes to pathogenicity. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (1); Glycosylation (3); Metal binding (6); Signal peptide (1)
Keywords Aminopeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Signal;Virulence;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 40,506
Kinetics
Metal Binding METAL 175; /note=Zinc 1; /evidence=ECO:0000250; METAL 194; /note=Zinc 1; /evidence=ECO:0000250; METAL 194; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 233; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 260; /note=Zinc 1; /evidence=ECO:0000250; METAL 338; /note=Zinc 2; catalytic; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda