| IED ID | IndEnz0002016256 |
| Enzyme Type ID | protease016256 |
| Protein Name |
Probable serine carboxypeptidase CPVL EC 3.4.16.- |
| Gene Name | cpvl DDB_G0274511 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MKVSLSFLLTILIVIITIKVNLSQEIKISPFFANNLKFEPIPDYIEYDSDSDAGEALFLSNYLDDHKTAKQKSCVDIGAPFQSCDKLLEIDSNLRDTEDFFTFTGFITVNETYNSNTFFWFLESQNGDKNSPLVIFLQGGPGGASTFSLFVETGPYELLDNFTLVQREITWNSEFAMLYIDNPVGTGFSFTDSQEGYSNNEDEIATNLYTFLQQFYKLYPEYYTNELYITGESYAGKYIPAFSYHIIQQNQNSNNPNINLKGIAIGDGLCDPITQVTQYANLAFYTGLADLQQQEVMFEYQDKIVEAINQEQWSVANDLFTDLINGPPDYFQNITGESDYYDIRKTVEPTYGGDFTAFLNQSSIRAMIHVGNNYFQNNNDVYIHLEQDIPKSVKQLFPTILDNIKVILYNGQFDFIVGPSLTETMIRTIEWEGIQPFLESPKIIWKIPSDNVDVAGFVRQWNSFTQVVVRQAGHMVPLDQPARAFDMIDRFINNEPFPSG |
| Enzyme Length | 500 |
| Uniprot Accession Number | Q869Q8 |
| Absorption | |
| Active Site | ACT_SITE 233; /evidence=ECO:0000250; ACT_SITE 414; /evidence=ECO:0000250; ACT_SITE 474; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.16.- |
| Enzyme Function | FUNCTION: May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (4); Propeptide (1); Signal peptide (1) |
| Keywords | Carboxypeptidase;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 18559084; 20422638; 22120990; |
| Motif | |
| Gene Encoded By | |
| Mass | 57,061 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |