| IED ID | IndEnz0002016276 |
| Enzyme Type ID | protease016276 |
| Protein Name |
ATP-dependent zinc metalloprotease FTSH 7, chloroplastic AtFTSH7 EC 3.4.24.- |
| Gene Name | FTSH7 At3g47060 F13I12.110 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MTTTFEFLQPRIHGFATCCSSNSLLYSKASRFFNDRCRVYRQNPNRFVSNSITLPLQKKQVTVLRNHERFNLWDGFSRKKSRLVVNCQEDDQNESSSEEEESSQSTPAKSERKREKKEDKVWWSKGKKWQWQPIIQAQGIGVLLLQLSVVMFVMRLLRPGIPLPGSEPRIQTTFVSVPYSEFLSKVNSNQVQKVEVDGVQVLFKLRDDGKWQESETSRLSQSSESLLRTVAPTKRVVYSTTRPGDIKTPYEKMLGNNVEFGSPEKRSGGFFNSALIALFYIAVLAGLIRFPVSFSTSSTGQLRTRKAGGPDGGKVSGGGETITFADVAGVDEAKEELEEIVEFLRNPEKYVRLGARPPRGVLLVGLPGTGKTLLAKAVAGEAEVPFISCSASEFVELYVGMGASRVRDLFARAKKEAPSIIFIDEIDAVAKSRDGKFRMGSNDEREQTLNQLLTEMDGFDSNSAVIVLGATNRADVLDPALRRPGRFDRVVTVETPDKIGRESILRVHVSKKELPLGDDVNLGSIASMTTGFTGADLANLVNEAALLAGRKNKTNVEKIDFIQAVERSIAGIEKKSARLKGNEKAVVARHEAGHAVVGTAVANLLTGQPRVEKLSILPRTGGALGFTYIPPTSEDRYLLFIDELLGRLVTLLGGRAAEEVVYSGRISTGAFDDIRRATDMAYKAVAEYGLNQKIGPVSVATLSGGGIDDSGGSPWGRDQGKLVDLVQKEVTILLQSALDVALSVVRANPDVLEGLGAQLEEKEKVEGEELQKWLSMVVAPEELAVFVEGKQELLLPAQASSS |
| Enzyme Length | 802 |
| Uniprot Accession Number | Q9SD67 |
| Absorption | |
| Active Site | ACT_SITE 591; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Probable ATP-dependent zinc metallopeptidase. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | NP_BIND 365..372; /note=ATP; /evidence=ECO:0000255 |
| Features | Active site (1); Chain (1); Metal binding (3); Nucleotide binding (1); Region (1); Transit peptide (2); Transmembrane (2) |
| Keywords | ATP-binding;Chloroplast;Hydrolase;Membrane;Metal-binding;Metalloprotease;Nucleotide-binding;Plastid;Protease;Reference proteome;Thylakoid;Transit peptide;Transmembrane;Transmembrane helix;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:14630971}; Multi-pass membrane protein {ECO:0000269|PubMed:14630971}; Stromal side {ECO:0000269|PubMed:14630971}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12185496; 12766230; 14576160; 17181860; 22121866; |
| Motif | |
| Gene Encoded By | |
| Mass | 87,802 |
| Kinetics | |
| Metal Binding | METAL 590; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 594; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 673; /note=Zinc; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda | 3.4.24.B20; |