| IED ID | IndEnz0002016284 |
| Enzyme Type ID | protease016284 |
| Protein Name |
Dipeptidyl-peptidase 5 EC 3.4.14.- Dipeptidyl-peptidase V DPP V DppV |
| Gene Name | SPBC1711.12 |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Enzyme Sequence | MHSLFKQLVFFLVMTLTAADKAAFDAESMLEAPRRSAVVSNPLGNLGIFIESNYSFADHKYNSGIYLLNESTRNHQELLVHGKSNKALTWITDSAFLYAREDNSSSSSILLFDVNNRSERIIYNHNSSISDIRIGEKNNHYRIVFSSVDNSLVKGPSNVHVYDHLFVRHWDRWNTGSRNTLYFIELDKKTENSNYFEISSEKAIDLLKETGLESPVEPFGGLSDFDSNYDKLVFVAKDPKLNPATQTKTVVYEINLNTRNLKSLSTAKGACSSPRLAKDGNHIAWLEMQTPQYESDQNQIMVYESESGAKKHIARHWDRSPSSIEWGVFKGGEPGLFAIAENYGKQILFFVSIFHHQVIPMTEEHSVSSISVPKSSSLWLTKSSLINPPYYAKINVETLNESVLLENNVGLSPTSYEEIWFPGTHGHRIHAWIVKPESFDKSKKYPVAVLIHGGPQGSWTDSWSTRWNPAVFANAGFIVFALDPTGSTGYGQRFTDSIALDWGGKPYKDIELGVEYIKNHLSYADSEKMVALGASYGGYMINWIQGHPLGRQFRALVCHDGVFNTLNTFYNTEELYFSIHDFGGTPWENRVIYERWNPSNFVNYWATPELVIHSSKDYRLTESEGIAAFNVLQYKGIPSRLLVFEDENHWVIKPDNSLRWHKEVLSWILHYTKDCNANEDETF |
| Enzyme Length | 683 |
| Uniprot Accession Number | Q9P778 |
| Absorption | |
| Active Site | ACT_SITE 535; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P23687; ACT_SITE 617; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P23687; ACT_SITE 649; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P23687 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.14.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (6); Signal peptide (1) |
| Keywords | Cytoplasm;Glycoprotein;Hydrolase;Nucleus;Protease;Reference proteome;Secreted;Serine protease;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 20473289; 22633491; 23173672; 23697806; 24727291; 25720772; |
| Motif | |
| Gene Encoded By | |
| Mass | 77,766 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |