| IED ID |
IndEnz0002016321 |
| Enzyme Type ID |
protease016321 |
| Protein Name |
Double-headed protease inhibitor, submandibular gland
|
| Gene Name |
|
| Organism |
Meles meles (Eurasian badger) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Sarcopterygii
Dipnotetrapodomorpha
Tetrapoda
Amniota
Mammalia
Theria
Eutheria
Boreoeutheria
Laurasiatheria
Carnivora
Caniformia
Mustelidae (weasel
mink
badger
martens and others)
Melinae
Meles
Meles meles (Eurasian badger)
|
| Enzyme Sequence |
APPPVGDQAGGRKVNCSKYNAKGSQFACSRHLDPVCGTDHRTYSNECMFCMLTQNKRFSVRILQDNNCDIECTQYSDMCTMDYLPLCGSDGNNYSNKCLFCNAVLRSRGALFLAKHGQCESP |
| Enzyme Length |
122 |
| Uniprot Accession Number |
P16226 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: This inhibitor is composed of two homologous actively inhibiting halves: one which inhibits trypsin, the other which inhibits elastase. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Disulfide bond (6); Domain (2); Site (2) |
| Keywords |
Direct protein sequencing;Disulfide bond;Protease inhibitor;Repeat;Secreted;Serine protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
13,534 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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