Detail Information for IndEnz0002016350
IED ID IndEnz0002016350
Enzyme Type ID protease016350
Protein Name Probable leucine aminopeptidase MCYG_04170
EC 3.4.11.-
Gene Name MCYG_04170
Organism Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Microsporum Arthroderma otae (Microsporum canis) Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Enzyme Sequence MKVLAALALSALALAKPTPPMPGMSLIQTGPQETRWVTDAEKLELTMNNVGFFDITDMPVTASSVTKPKSYAFPGNVSHQADVKPLLGKLSSDHLMSNLQKFSDFPNRYYQADTGVQSAEWVLSQVQGVIGKIQGAKAEKIEHKWKQPSIRAIIPGKSEKIVVVGAHQDSINGQNPKAAAPGADDNGSGSMTILEALTALVSDQKIAGGQATNTIEFHWYAGEEAGLLGSQAVFQQYKQAGKEVVAMLNQDMTGYGKTMGIITDNSDSALTTFTKMILDTYTTAKYADSECGYACSDHASANKAGYPSAFVYEAVLGQDNPAIHSPDDTIDKLDPAKMLEHAKLVVGFAYELAFANL
Enzyme Length 357
Uniprot Accession Number C5FNB5
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.11.-
Enzyme Function FUNCTION: Probable extracellular aminopeptidase which contributes to pathogenicity. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (1); Glycosylation (2); Metal binding (6); Signal peptide (1)
Keywords Aminopeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Signal;Virulence;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 38,225
Kinetics
Metal Binding METAL 167; /note=Zinc 1; /evidence=ECO:0000250; METAL 185; /note=Zinc 1; /evidence=ECO:0000250; METAL 185; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 224; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 251; /note=Zinc 1; /evidence=ECO:0000250; METAL 324; /note=Zinc 2; catalytic; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda