Detail Information for IndEnz0002016358
IED ID IndEnz0002016358
Enzyme Type ID protease016358
Protein Name Carboxypeptidase 2
EC 3.4.17.-
Carboxypeptidase M14B
Carboxypeptidase MCPB
Gene Name MCPB CARB2
Organism Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum)
Enzyme Sequence MVAYRFLTLISLGLGSHCVSALQYGYNQLSTHKDPAVVAGAFPAINGTHLRSPAFTSPGTVSRGFSDGTSGPTRDETMEGFMRRLARSNSWMAYHEAGFKSEEGRKFPYMYLSASSSSVENPSSRKLRVWLQGGVHGNEPAGDQSMLVLLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHLKLARQQTRDIKELFAKFSPHIATDMHEFTAGRAFGPKKDFIYAADALFSAAKNLNIDEGIRQLSEKLFAKRMGKDIEAAGLRWDPYITLGESSSSKLLLREAGTDAKIGRNAMGLSQCVVFLCETRGIGIADQHFERRTLSGLVMAKSVLQTAVDNFDEVYNTIERGIRRFTNSRNDIVLTDKSPIIERTFGMLNTTDASLFDYPIDFATTTPAEPVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEFYEGVVTTTVETKLVERSIRLPPGSYLVKTNQKNAALAFVALEPENIDSFASFGIIPVNTGDQYPIFRLK
Enzyme Length 538
Uniprot Accession Number A6XHF7
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.17.-
Enzyme Function FUNCTION: Extracellular metalloprotease that contributes to pathogenicity. {ECO:0000269|PubMed:18222721}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Compositional bias (1); Glycosylation (3); Region (1); Signal peptide (1)
Keywords Carboxypeptidase;Glycoprotein;Hydrolase;Protease;Secreted;Signal;Virulence
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18222721}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 59,861
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda