IED ID | IndEnz0002016358 |
Enzyme Type ID | protease016358 |
Protein Name |
Carboxypeptidase 2 EC 3.4.17.- Carboxypeptidase M14B Carboxypeptidase MCPB |
Gene Name | MCPB CARB2 |
Organism | Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Trichophyton rubrum (Athlete's foot fungus) (Epidermophyton rubrum) |
Enzyme Sequence | MVAYRFLTLISLGLGSHCVSALQYGYNQLSTHKDPAVVAGAFPAINGTHLRSPAFTSPGTVSRGFSDGTSGPTRDETMEGFMRRLARSNSWMAYHEAGFKSEEGRKFPYMYLSASSSSVENPSSRKLRVWLQGGVHGNEPAGDQSMLVLLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHLKLARQQTRDIKELFAKFSPHIATDMHEFTAGRAFGPKKDFIYAADALFSAAKNLNIDEGIRQLSEKLFAKRMGKDIEAAGLRWDPYITLGESSSSKLLLREAGTDAKIGRNAMGLSQCVVFLCETRGIGIADQHFERRTLSGLVMAKSVLQTAVDNFDEVYNTIERGIRRFTNSRNDIVLTDKSPIIERTFGMLNTTDASLFDYPIDFATTTPAEPVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEFYEGVVTTTVETKLVERSIRLPPGSYLVKTNQKNAALAFVALEPENIDSFASFGIIPVNTGDQYPIFRLK |
Enzyme Length | 538 |
Uniprot Accession Number | A6XHF7 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.17.- |
Enzyme Function | FUNCTION: Extracellular metalloprotease that contributes to pathogenicity. {ECO:0000269|PubMed:18222721}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Compositional bias (1); Glycosylation (3); Region (1); Signal peptide (1) |
Keywords | Carboxypeptidase;Glycoprotein;Hydrolase;Protease;Secreted;Signal;Virulence |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:18222721}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..21; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 59,861 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |