IED Industry Enzyme Database

Detail Information for IndEnz0002016496
IED ID IndEnz0002016496
Enzyme Type ID protease016496
Protein Name Collagen alpha-1
I
chain
Alpha-1 type I collagen
Gene Name COL1A1
Organism Homo sapiens (Human)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human)
Enzyme Sequence MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL
Enzyme Length 1464
Uniprot Accession Number P02452
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Type I collagen is a member of group I collagen (fibrillar forming collagen).
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (14); Chain (1); Compositional bias (6); Disulfide bond (5); Domain (2); Erroneous initiation (1); Glycosylation (3); Helix (6); Metal binding (5); Modified residue (125); Motif (2); Natural variant (168); Propeptide (2); Region (4); Sequence conflict (11); Signal peptide (1); Site (3); Turn (2)
Keywords 3D-structure;Calcium;Chromosomal rearrangement;Collagen;Direct protein sequencing;Disease variant;Disulfide bond;Dwarfism;Ehlers-Danlos syndrome;Extracellular matrix;Glycoprotein;Hydroxylation;Metal-binding;Osteogenesis imperfecta;Phosphoprotein;Pyrrolidone carboxylic acid;Reference proteome;Repeat;Secreted;Signal
Interact With P08123; P02751; Q14145; O01949
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
Modified Residue MOD_RES 162; /note=Pyrrolidone carboxylic acid; /evidence=ECO:0000269|PubMed:5529814; MOD_RES 170; /note=Allysine; /evidence=ECO:0000269|PubMed:5529814; MOD_RES 171; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02454; MOD_RES 190; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 193; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 196; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 205; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 208; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 211; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 226; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 241; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 247; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 256; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 262; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 265; /note=5-hydroxylysine; alternate; /evidence=ECO:0000269|PubMed:4319110; MOD_RES 271; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02454; MOD_RES 289; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 292; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 298; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 307; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 313; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 334; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 343; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 346; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 373; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 376; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 388; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 394; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 403; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 409; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 412; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 427; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 430; /note=5-hydroxylysine; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 436; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 439; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 451; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 460; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 475; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 481; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 490; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 496; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 505; /note=5-hydroxylysine; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 514; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 523; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 529; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 535; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 544; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 547; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 556; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 565; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 571; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 583; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 592; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 601; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 604; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 622; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 640; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 646; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 652; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 658; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 664; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 670; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 682; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 691; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 703; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 715; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 718; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 724; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 730; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 739; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 751; /note=5-hydroxylysine; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 757; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 772; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 778; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 787; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02454; MOD_RES 799; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 805; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 808; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 817; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 823; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 841; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 850; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 859; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 862; /note=5-hydroxylysine; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 871; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 877; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 885; /note=3-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 886; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 895; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 898; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 919; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 928; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 937; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 946; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 964; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 973; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 976; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 982; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 997; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1003; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1009; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1018; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1024; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1033; /note=5-hydroxylysine; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1045; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1048; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1051; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1096; /note=5-hydroxylysine; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1108; /note=5-hydroxylysine; alternate; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1120; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1123; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1126; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1144; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P02457; MOD_RES 1159; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1164; /note=3-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1165; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1179; /note=3-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1180; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1182; /note=3-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1183; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1185; /note=3-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1186; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1189; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1192; /note=4-hydroxyproline; /evidence=ECO:0000250|UniProtKB:P11087; MOD_RES 1208; /note=Allysine; /evidence=ECO:0000250|UniProtKB:P02453
Post Translational Modification PTM: Contains mostly 4-hydroxyproline. Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. {ECO:0000269|PubMed:4319110}.; PTM: Contains 3-hydroxyproline at a few sites. This modification occurs on the first proline residue in the sequence motif Gly-Pro-Hyp, where Hyp is 4-hydroxyproline. {ECO:0000250|UniProtKB:P11087}.; PTM: Lysine residues at the third position of the tripeptide repeating unit (G-X-Y) are 5-hydroxylated in some or all of the chains. {ECO:0000269|PubMed:4319110}.; PTM: O-glycosylated on hydroxylated lysine residues. The O-linked glycan consists of a Glc-Gal disaccharide. {ECO:0000269|PubMed:4319110}.
Signal Peptide SIGNAL 1..22
Structure 3D NMR spectroscopy (1); Electron microscopy (2); X-ray crystallography (10)
Cross Reference PDB 1Q7D; 2LLP; 3EJH; 3GXE; 5CTD; 5CTI; 5CVA; 5CVB; 5K31; 5OU8; 5OU9; 7E7B; 7E7D;
Mapped Pubmed ID 10025922; 10084560; 10479448; 10521801; 10551873; 10566692; 10596943; 10627461; 10686426; 10809722; 10887121; 10913946; 10934207; 11084047; 11085801; 11090261; 11106645; 11122085; 11136533; 11173011; 11204438; 11230734; 11259413; 11303720; 11310843; 11316004; 11383910; 11420783; 11432962; 11481033; 11508783; 11518510; 11547828; 11547832; 11566920; 11572855; 11577169; 11668615; 11683425; 11685422; 11700320; 11716195; 11731270; 11792589; 11874231; 11907712; 11973338; 12016463; 12016466; 12034531; 12069607; 12072442; 12073153; 12096841; 12099690; 12101112; 12107666; 12127408; 12138160; 12164934; 12185380; 12200454; 12211432; 12211646; 12225811; 12232678; 1237296; 12393937; 12447604; 12475640; 12491092; 12496264; 12575457; 12584032; 12590186; 12646579; 12753258; 12787275; 12803121; 12810179; 12855811; 12868700; 12879219; 1323838; 1348714; 1400327; 14500733; 14506618; 14528100; 14562991; 14595528; 14613485; 14633859; 14643521; 14672895; 14698296; 14722584; 14734826; 1484505; 15044469; 15049048; 15075323; 15081423; 15085313; 15106082; 15133851; 15155468; 15211650; 15227656; 15241219; 15241796; 15256976; 15257288; 15365990; 1544908; 15466008; 15514164; 15514891; 15552843; 15570400; 15581348; 15592793; 15638371; 1567360; 15703183; 1577494; 15781005; 15788405; 15794927; 15837520; 15880349; 15950180; 15952128; 15965952; 15966503; 15994869; 16001263; 16009674; 16102041; 16102727; 16114814; 16159929; 16171977; 16173077; 16263577; 16272059; 16272566; 16278217; 16293224; 16407265; 16410344; 16458627; 16475872; 16498072; 16521042; 16540720; 16563355; 16580273; 16591531; 16622736; 16713399; 16723701; 16782899; 16804049; 16806867; 16815299; 16825197; 16831952; 16835341; 16864092; 16869454; 16911569; 16934803; 16988190; 17019952; 17021946; 17028262; 17100549; 17135298; 17140440; 171650; 17179726; 17187960; 17201588; 17252541; 17273809; 17276428; 17303000; 17331078; 17332715; 17392686; 17460886; 17489845; 17551768; 17554369; 17557158; 17588949; 17698844; 17766609; 17876648; 17889845; 17903305; 17950782; 17991736; 18024269; 18028452; 18089612; 18209062; 18226133; 18298657; 18306915; 18311573; 18323784; 18353721; 18361931; 18379465; 18380967; 18401458; 18412368; 18487197; 18536987; 18550494; 18551240; 18580957; 18599485; 18619040; 18634290; 18644377; 18669982; 18681778; 18682895; 18694864; 18703872; 18704262; 18709850; 1874735; 18787532; 18818748; 18836165; 18925325; 19013156; 19016596; 19019335; 19031824; 19071236; 19075007; 19082910; 19110771; 19143970; 19145934; 19172220; 19193663; 19193665; 19206162; 19251642; 19255718; 19259350; 19260140; 19299182; 19306436; 19341834; 19358256; 19387081; 1939645; 19409513; 19418583; 19429913; 19453261; 19465003; 19491628; 19506792; 19527514; 19558215; 19595020; 19635106; 19655227; 19675556; 19700402; 19714363; 19718407; 19734317; 19751715; 1975693; 19789904; 19813243; 19861282; 19890351; 19893454; 19913121; 19913496; 19929435; 19932771; 20015075; 20015871; 20045402; 20061935; 20063990; 20087402; 2010539; 20133221; 20140262; 20146006; 20146870; 20191437; 20235194; 20237151; 20359090; 20369485; 20379614; 20406730; 20435445; 20444423; 20452482; 20463013; 20470363; 20489157; 20509788; 20532479; 20543003; 20571774; 2059554; 20628086; 20651840; 20673868; 20686481; 20693403; 20704113; 20711500; 20721936; 20724381; 20730098; 20730440; 20736093; 20798928; 20961463; 21029365; 21033393; 21042785; 21085489; 21095332; 21111450; 21113976; 21134900; 21163673; 21178584; 21215393; 21302452; 21311138; 21336691; 21341209; 21343850; 21405976; 21462477; 21535073; 21558934; 21564311; 21647970; 21667357; 21690299; 21702901; 21713451; 21746880; 21764694; 21777208; 21789315; 21834035; 21841309; 21874239; 21878990; 21935919; 21967573; 21970315; 22054507; 22057139; 22130917; 22139845; 22174012; 22190259; 22210296; 22219633; 22239621; 22249249; 22297492; 22337942; 22367096; 22422640; 22434650; 22489040; 22565191; 22575643; 22576977; 22645275; 22679784; 22694915; 22829018; 22871215; 22987783; 22999338; 2300123; 23013730; 23040566; 23068445; 23079818; 23137636; 23159876; 23168334; 23199263; 23207290; 23276824; 23338998; 23341452; 23418565; 23418792; 23517059; 23529829; 23546968; 23548228; 23592926; 23601588; 23624467; 23639859; 2364322; 23653354; 23682108; 23731614; 23749290; 23754495; 23763354; 23800666; 23858805; 23906792; 23918805; 23925543; 23941072; 24072491; 24088220; 24147872; 24170657; 24227918; 24286194; 24289089; 2430969; 24361166; 24390061; 24398012; 24434151; 24552139; 24559391; 24566004; 24637022; 24668929; 24711029; 24742993; 24767406; 24802400; 24804200; 24835590; 24891183; 24909851; 25025981; 25091173; 25107895; 25119913; 25142742; 25190218; 25251588; 25290767; 25324685; 25342482; 25400810; 25414072; 25432063; 2543975; 25449076; 25467797; 25502582; 2551898; 25521223; 25536346; 25554417; 25562121; 25575822; 25683993; 25692237; 25696019; 25716998; 25816734; 25873777; 25924890; 25944380; 26003732; 26044709; 26051322; 26192994; 26199386; 26260940; 26288845; 26308289; 26337045; 26383724; 26393468; 26400328; 26403314; 26423565; 26452701; 26478226; 26634493; 26645431; 26694865; 26712438; 26727275; 26752685; 26848503; 26852534; 26857861; 26861712; 26887942; 26894886; 26926600; 26927310; 26932148; 26935598; 26995940; 27044453; 27060301; 27090748; 27105433; 27132807; 27178384; 27298363; 27322414; 27363273; 27371342; 27454992; 27477081; 27484908; 27503584; 27511505; 27519266; 27521280; 27549894; 27577215; 27595307; 27609069; 27632864; 27636223; 27655672; 27691923; 27748872; 27840329; 27894325; 27897211; 28102596; 28130256; 28177155; 28206959; 28258342; 28259900; 28261929; 28281531; 28286269; 28302318; 28334615; 28339802; 2834383; 28370352; 28428367; 28432057; 2845110; 28498836; 28526934; 28528406; 28569392; 28629592; 28796060; 28810924; 28827734; 28981938; 28983623; 29068597; 29101475; 29196165; 29199991; 29393423; 29520684; 29543232; 29543922; 29568927; 29594386; 29641324; 29669177; 29763968; 29781507; 29906404; 2991928; 29980413; 30044046; 30132520; 30227844; 30251958; 30272346; 30272615; 30273997; 30310058; 30348200; 30358549; 30388611; 3038863; 30389107; 30475338; 30483853; 30515401; 30604926; 30664222; 30683734; 31034464; 31055083; 31128912; 31159867; 31204718; 31239369; 31246104; 31308468; 31531849; 3155520; 3159726; 31661146; 31677274; 3173483; 31769248; 31794058; 31870844; 31876392; 31887804; 31901757; 31902369; 31957232; 32017203; 32034735; 32091183; 32157177; 32165296; 32166892; 32234057; 32323045; 32335875; 32379989; 32406547; 32419506; 32442272; 32588564; 32589888; 32692893; 32909608; 33053334; 33118184; 33226850; 33261612; 33339581; 33345281; 33358398; 33409715; 33446772; 33451138; 33489015; 33490271; 33550735; 33650641; 33672311; 33692215; 33731655; 33780362; 33893003; 33896817; 34261485; 34290266; 34371012; 34727246; 34867934; 3595596; 3872140; 3872795; 3905801; 3992061; 41816; 5246001; 5723342; 6129847; 6270089; 641035; 6439184; 6809411; 710450; 7738948; 7852349; 7890717; 8034572; 8129781; 8144597; 8207089; 8440685; 8463259; 8576151; 8617742; 8631758; 8920930; 8943283; 8999957; 9028946; 9054364; 9092507; 9252349; 9295288; 9425086; 9433891; 9470928; 9545296; 9560306; 9582318; 9651395; 9659899; 9659900; 9685393; 9752968; 9798967;
Motif MOTIF 745..747; /note=Cell attachment site; /evidence=ECO:0000255; MOTIF 1093..1095; /note=Cell attachment site; /evidence=ECO:0000255
Gene Encoded By
Mass 138,911
Kinetics
Metal Binding METAL 1277; /note=Calcium; /evidence=ECO:0000250; METAL 1279; /note=Calcium; /evidence=ECO:0000250; METAL 1280; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000250; METAL 1282; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000250; METAL 1285; /note=Calcium; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda