IED ID |
IndEnz0002016510 |
Enzyme Type ID |
protease016510 |
Protein Name |
Angiotensin-1-converting enzyme inhibitory peptide
|
Gene Name |
|
Organism |
Macrocybe gigantea (Giant mushroom) (Tricholoma giganteum) |
Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Basidiomycota
Agaricomycotina
Agaricomycetes
Agaricomycetidae
Agaricales
Catathelasmataceae
Macrocybe
Macrocybe gigantea (Giant mushroom) (Tricholoma giganteum)
|
Enzyme Sequence |
GEP |
Enzyme Length |
3 |
Uniprot Accession Number |
P84761 |
Absorption |
|
Active Site |
|
Activity Regulation |
|
Binding Site |
|
Calcium Binding |
|
catalytic Activity |
|
DNA Binding |
|
EC Number |
|
Enzyme Function |
FUNCTION: Inhibits competitively angiotensin I-converting enzyme. Administration to hypertensive rats at a dosage of 1 mg/kg results in a decrease in blood pressure. {ECO:0000269|PubMed:15165718}. |
Temperature Dependency |
|
PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Peptide (1) |
Keywords |
Direct protein sequencing;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor |
Interact With |
|
Induction |
|
Subcellular Location |
|
Modified Residue |
|
Post Translational Modification |
|
Signal Peptide |
|
Structure 3D |
|
Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
|
Gene Encoded By |
|
Mass |
301 |
Kinetics |
|
Metal Binding |
|
Rhea ID |
|
Cross Reference Brenda |
|