| IED ID |
IndEnz0002016516 |
| Enzyme Type ID |
protease016516 |
| Protein Name |
Alpha-2-macroglobulin
|
| Gene Name |
XF_1252 |
| Organism |
Xylella fastidiosa (strain 9a5c) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Proteobacteria
Gammaproteobacteria
Xanthomonadales
Xanthomonadaceae
Xylella
Xylella fastidiosa
Xylella fastidiosa (strain 9a5c)
|
| Enzyme Sequence |
MRDRVAMMLRPLVRGWIPRAVLLLTVAFSFGCNRNHNGQLPQSSGEPVAVAKEPVKGFVLVRAYPDQHDGELALALEFSQPLAATQEFDTLVRLEQDSGNHDGGWSLSDDAKTLRYPYVEADKHYTVLISAGLLAATGSRLGKPRKEPVYTGELDPVVGFASRGSILPARGSRGVPVVSVNVPEVDVEFMRVREKALPAFLARYHKAGQRSSWELSNQGNSRKRLSELADPVYVTRFVLDGKKNERALTYLPIQSIRELREPGLYFAVMKPTGSFSDAFETAFFSVSNIGLHTRAYKDKLFVHTASLRSGNPYKQVDLLVLDAKGETVLQGATDDNGNALLNYTLNAGHVLVSRNGRDISILPFNQPALDLSEFAVAGRENPWFDVFAWSGRDLYRPGETLRISALLRDRDGKPVKPQPVFLRLKQPDGKTFRETRLQPAEQGYLEFTQKIPSDAPTGRWRVEFRTDPASKEAVQGLAVRVEEFLPERMKLELSSAQPVLRAKAPFTLTADAAYLYGAPAAGNRFTANLAVAVEQHPLDNMPGWFFGDATLQLPRGAKETIDITLGADGHLVHDIVLPEEAKPVSPMAVVVSGSVYESGGRPVTRSLKRVLWPADALVGVRPLFDVASGADANGMARFELTRVGVDGKPQSAKGLKATLVRELRDYHWRYSDGRWDYDFTRRFENKETRTVDISTSHTTTLALPVEWGDYRLEVFDPVTGLTMRYPFRAGWSWGDDNRGLDARPDKVKLALDKTSYRAGDTLKVTITPPHPGKGLLLVESDKPLYVQAIDANPSTTLEIPVTADWERHDVYVTALVFRGGSASNNTTPARAVGEVYVPMQRKDRRVAVGLVVPKQMRPAQSLPVTVSVPELAGKQAHVTISAVDAGILNITGFPVPDAAAHFFAQRRLSVDAYDIYGRVIESFEGGTGRLKFGGDMALPPLPQAKRPTARSQTVDLFSGAVKLDAKGNAHIQLPVPDFNGALRVSALVYSDTRYGQRDAETVVRAPILAEASMPRVMAPGDRSTVTVDVQNFTGKQGKFAVKVEGVGPLAVAEAGRSVTLGIDGKTTLNFPLRALEGNSVAQVRVRVEGNGSKAERHYDLPVRAAWPQGLRTQAHVLNVLAPIAFDPALAKGLMPDSVNARLSVSALAPIPFASVLQGVFEYPYGCAEQTASKGYAALWLDDATIKSLGIHGVTPAQRLERLEGALGRLASLQTMNGHFSMCGGNSDVNPVLTPYIAGFLLDAKDAGFAVSDAVLQKALNRLSEDLLSGAHLFYGNDQSEALMFAHQAWSGYVLARVNRAPLGTLRTLYDNERGKAVSGLSLVHLGVALSLQGDRKRGEAAIEAGFAKSEGGRPEVFGDYGSVIRDNALMIALVRAHGLAKPAYEARVMALGRDLEARRRSGWLWLSTQEQVALAQLGRALLVDQKKQVSGTLYVGKQREEIAASRLIGRSFDAAALARGVRFVPQGDVPLYASFEVAGIPRQAPVSDDSQLLVVRRWYTVDGKPWTPGPLKEGQALIVRVSVTSKQNMPDALLTDLLPAGLEIDNFNLGETRQWADVTVDGIALSERANAADIKHEEFRDDRYVAMLQLTGGRTANLFYLVRAVTPGTYKVPPSLVEDMYRPALRGTGRVAPATVTVVQP |
| Enzyme Length |
1641 |
| Uniprot Accession Number |
Q9PDX7 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Protects the bacterial cell from host peptidases. {ECO:0000250|UniProtKB:P76578}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Cross-link (1); Lipidation (2); Signal peptide (1) |
| Keywords |
Cell membrane;Lipoprotein;Membrane;Palmitate;Protease inhibitor;Reference proteome;Signal;Thioester bond |
| Interact With |
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| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..31; /evidence=ECO:0000255|PROSITE-ProRule:PRU00303 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
|
| Mass |
178,922 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
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| Cross Reference Brenda |
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