Detail Information for IndEnz0002016642
IED ID IndEnz0002016642
Enzyme Type ID protease016642
Protein Name Carbohydrate-binding protein AQN-1
Spermadhesin AQN-1
Zona pellucida-binding protein AQN-1
Gene Name
Organism Sus scrofa (Pig)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Suina Suidae (pigs) Sus Sus scrofa (Pig)
Enzyme Sequence AQNKGPHKCGGVLRNYSGRISTYEGPKTDCIWTILAKPGSRVFVAIPYLNLACGKEYVEVQDGLPGAGNYGKLCSGIGLTYQSSSNALSIKYSRTAGHSASSFDIYYYGDS
Enzyme Length 111
Uniprot Accession Number P26322
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: AQN proteins mediate the binding of boar spermatozoa to component(s) of the egg's zona pellucida by a carbohydrate-binding mechanism. AQN proteins are secretory components of the male accessory glands being coated to the sperm surface at the time of ejaculation. They possess as well heparin-, serine-protease-inhibitor-binding capability.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (2); Domain (1); Modified residue (1); Sequence conflict (2)
Keywords Acetylation;Direct protein sequencing;Disulfide bond;Fertilization;Heparin-binding;Reference proteome;Secreted
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue MOD_RES 1; /note=N-acetylalanine; /evidence=ECO:0000250|UniProtKB:P26776
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 11,882
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda