Detail Information for IndEnz0002016650
IED ID IndEnz0002016650
Enzyme Type ID protease016650
Protein Name Probable Xaa-Pro aminopeptidase P
AMPP
Aminopeptidase P
EC 3.4.11.9
Aminoacylproline aminopeptidase
Prolidase
Gene Name AMPP MGYG_04346
Organism Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Nannizzia Arthroderma gypseum (Microsporum gypseum) Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum)
Enzyme Sequence MTILRHPLRFLFKPRFLYFQSPSGQSSRPFSTSQILRTALDMPPPPVDTTQRLAKLRELMAQNKVDVYTFISSFTGSAGCAIVSMSKAALSTDGRYFSQAAKQLDSNWTLLKRGVEGVPTWEEWTAEQAENGKVVGVDPSLITAADARKLSQTLKTTGGSLIGIDQNLIDAVWGDERPARPSNQITVQPVERAGKSFEEKVEDLRKELAAKKRSAMVISTLDEIAWLFNLRGSDIPYNPVFFSYAIVTPSVAELYVDENKLSPEARKHLEGKVVLKPYESIFQASKALAESKASASSGSGGKFLLSNKASWSVSLALGGEQNVVEVRSPITDAKAIKNEVELEGFRKCHIRDGAALIEYFAWLENALIKEGAKLDEVDGANKLFEIRKKYDHFVGNSFDTISSTGANGATIHYKPEKSTCAVIDPKAMYLCDSGGQYLDGTTDTTRTLHFGEPTEFQKKAYALVLKGHISIDNAIFPKGTTGYAIDSFARQHLWKEGLDYLHGTGHGVGSFLNVHEGPMGIGSRAQYAEVPLSASNVLSNEPGYYEDGNFGIRLENLVICKEVKTPHKFGDKPFLGFEYITLVPFCQKLLDASLLTEAERKWVNDYHAKVWEKTSPFFEKDELTTNWLKRETQPI
Enzyme Length 635
Uniprot Accession Number E4USI8
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9;
DNA Binding
EC Number 3.4.11.9
Enzyme Function FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (6)
Keywords Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 70,370
Kinetics
Metal Binding METAL 432; /note=Manganese 2; /evidence=ECO:0000250; METAL 443; /note=Manganese 1; /evidence=ECO:0000250; METAL 443; /note=Manganese 2; /evidence=ECO:0000250; METAL 541; /note=Manganese 1; /evidence=ECO:0000250; METAL 555; /note=Manganese 1; /evidence=ECO:0000250; METAL 555; /note=Manganese 2; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda