Detail Information for IndEnz0002016651
IED ID IndEnz0002016651
Enzyme Type ID protease016651
Protein Name Probable Xaa-Pro aminopeptidase P
AMPP
Aminopeptidase P
EC 3.4.11.9
Aminoacylproline aminopeptidase
Prolidase
Gene Name ampp app AO090701000720
Organism Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus oryzae (Yellow koji mold) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Enzyme Sequence MLFSRPPIRSPWISAFRSASQLPLSRPRFFSISLSRYSVDMETVNTSERLSRLRELMQEHKVDVYIVPSEDSHQSEYIAPCDGRREFISGFSGSAGTAIVSLSKAALSTDGRYFNQASKQLDNNWQLLKRGVEGFPTWQEWTTEQAEGGKVVGVDPALITASGARSLSETLKKNGSTLVGVQQNLVDLVWGKDRPAPPREKVRVHPEKYAGKSFQEKISELRKELESRKSAGFIVSMLDEIAWLFNLRGSDIPYNPVFFSFATITPTTTELYVDADKLTPEVTAHLGQDVVIKPYDAIYADAKALSETRKQEAGETASKFLLSNKASWALSLSLGGEGQVEEVRSPIGDAKAVKNDVELAGMRACHIRDGAALTEYFAWLENELVNKKSTLDEVDAADKLEQIRSKHDLFVGLSFDTISSTGPNGAVIHYKPEKGSCSIIDPNAIYLCDSGAQYLDGTTDVTRTFHFGQPTELEKKAFTLVLKGVIGLDTAVFPKGTSGFALDVLARQYLWKEGLDYLHGTGHGIGSYLNVHEGPIGVGTRVQYTEVPIAPGNVISDEPGFYEDGKFGIRIENVIMAREVQTTHKFGDKPWLGFEHVTMAPIGRNLIEPSLLSDAELKWVNDYHREIWEKTHHFFENDEYTRSWLQRETQPISK
Enzyme Length 654
Uniprot Accession Number Q2U7S5
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9;
DNA Binding
EC Number 3.4.11.9
Enzyme Function FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Erroneous gene model prediction (1); Metal binding (6); Sequence conflict (1)
Keywords Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 72,826
Kinetics
Metal Binding METAL 449; /note=Manganese 2; /evidence=ECO:0000250; METAL 460; /note=Manganese 1; /evidence=ECO:0000250; METAL 460; /note=Manganese 2; /evidence=ECO:0000250; METAL 558; /note=Manganese 1; /evidence=ECO:0000250; METAL 572; /note=Manganese 1; /evidence=ECO:0000250; METAL 572; /note=Manganese 2; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda 3.4.11.9;