Detail Information for IndEnz0002016661
IED ID IndEnz0002016661
Enzyme Type ID protease016661
Protein Name Probable Xaa-Pro aminopeptidase CPSG_02684
EC 3.4.11.9
Aminoacylproline aminopeptidase
Prolidase
Gene Name CPSG_02684
Organism Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Onygenales incertae sedis Coccidioides Coccidioides posadasii (Valley fever fungus) Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus)
Enzyme Sequence MAGSNTLSSSEHGDDPRGHSYSIHIQTRGTTLDKYPAKQHARNVARQLGLTDGLIYLMSQSTRTLEDSDQPQPFRQRRYFFYLSGVDEPDCHLTFDIKSDILTLYVPHYDLRKAIWVGPTLRPSEAMMRYDLNAAKTYDELSKNIRTWASKRMSPVIYILHEGQKPNINAHFLAFNHEDLLPAMDACREIKDEHEIDLIRRANEISASAHIEVLLGIRNMQNEAEIHGKFLDTCVSQGARNQSYEIIAASGENAAILHYTKNNEPLDDRQLVCLDAGAEWNCYASDVTRTFPRRPYWPSCESANIYSVVQRMQEECINGLKEGVRYLDLHILAHRIAIEELLSLGILKGGSTEEILQSGASLVFFPHGLGHHVGLEVHDVSPTPLMAFSLDKYKGLPLLSCRPPCTLSAPYLKAGMVVTVEPGIYFSRPALKDARRKPLSKYIDMDVVQKYIPVGGVRIEDDVLVTRDGFENLTKAPKGREMLKTIR
Enzyme Length 487
Uniprot Accession Number E9CY14
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9;
DNA Binding
EC Number 3.4.11.9
Enzyme Function FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (6); Region (1)
Keywords Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 54,966
Kinetics
Metal Binding METAL 275; /note=Manganese 2; /evidence=ECO:0000250; METAL 286; /note=Manganese 1; /evidence=ECO:0000250; METAL 286; /note=Manganese 2; /evidence=ECO:0000250; METAL 421; /note=Manganese 1; /evidence=ECO:0000250; METAL 460; /note=Manganese 1; /evidence=ECO:0000250; METAL 460; /note=Manganese 2; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda