| IED ID | IndEnz0002016701 |
| Enzyme Type ID | protease016701 |
| Protein Name |
Probable Xaa-Pro aminopeptidase pepP EC 3.4.11.9 Aminoacylproline aminopeptidase Prolidase |
| Gene Name | pepP PMAA_069810 |
| Organism | Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) (Penicillium marneffei) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Trichocomaceae Talaromyces Talaromyces sect. Talaromyces Talaromyces marneffei (Penicillium marneffei) Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) (Penicillium marneffei) |
| Enzyme Sequence | MTSTDGILAGKYPAKAHARRVVEYLRQNGFQGDGVLYLEAQKTRMIEDNDSEQPFRQRRFFFYLSGCLLPDAHLTYHISTDKLTLFIPPLDPESVIWSGLPLSPAQAKELYDVDEVLYTTDVNPTLAHLASKVGFVFAIDGQISDDVSLKSFPDTDKVALKTAIEECRAVKDAYEVAMIRKANDVTSQAHVAVLKAAKSATNERELEAAFIGTCIAQGCREMAYHPIVASGTSSATLHYVNNDEPLIDSSTNKKKLNLLLDAAGEYKAYCADVTRTFPLSGKFSPESREIYDIVLEMQTESLAMLKEGVLWEDVHITAHRVAIKGLLKLGILRGSEEELLEKRVSVAFFPHGLGHYLGMDTHDTGGHANYADKDKMFQYLRVRGKLPAGSVITVEPGVYFCRFIIEPYLKDSELSKYIDADVLEKYWEVGGVRIEDNIHITKEGHENLTTAPKTADQVELMINGS |
| Enzyme Length | 465 |
| Uniprot Accession Number | B6Q8T5 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9; |
| DNA Binding | |
| EC Number | 3.4.11.9 |
| Enzyme Function | FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (6) |
| Keywords | Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 51,734 |
| Kinetics | |
| Metal Binding | METAL 261; /note=Manganese 2; /evidence=ECO:0000250; METAL 272; /note=Manganese 1; /evidence=ECO:0000250; METAL 272; /note=Manganese 2; /evidence=ECO:0000250; METAL 395; /note=Manganese 1; /evidence=ECO:0000250; METAL 435; /note=Manganese 1; /evidence=ECO:0000250; METAL 435; /note=Manganese 2; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |