Detail Information for IndEnz0002016717
IED ID IndEnz0002016717
Enzyme Type ID protease016717
Protein Name Aminopeptidase T
AP-T
EC 3.4.11.-
Heat-stable aminopeptidase
Gene Name TTHA1152
Organism Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Deinococcus-Thermus Deinococci Thermales Thermaceae Thermus Thermus thermophilus Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Enzyme Sequence MDAFKRNLEKLAELAIRVGLNLEKGQEVIATAPIEAVDFVRLLAEKAYREGASLFTVIYGDQELARKRLALAPEEGLDKAPAWLYEGMARAFREGAARLAVSGSDPKALEGLPPEKVGRAQKANARAYKPALEAITEFVTNWTIVPFAHPGWARAVFPGLPEEEAVRRLWEAIFQATRADQEDPIAAWEAHNRALHEKVAYLNARRFHALHFKGPGTDLVVGLAEGHLWQGGATATKGGRLCNPNLPTEEVFTAPHRERVEGVVRASRPLALGGTLVEGIFARFERGFAVEVRAEKGEEVLRRLLDTDEGARRLGEVALVPADNPIAKTGLVFFDTLFDENAASHIAFGQAYQENLEGRPSGEAFRKRGGNESLVHVDWMIGSEEMDVDGLYEDGTRTPLMRRGRWVV
Enzyme Length 408
Uniprot Accession Number P42778
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.11.-
Enzyme Function FUNCTION: Metal-dependent exopeptidase. {ECO:0000269|PubMed:16242715}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Metal binding (8)
Keywords 3D-structure;Aminopeptidase;Cobalt;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D X-ray crystallography (1)
Cross Reference PDB 2AYI;
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,018
Kinetics
Metal Binding METAL 250; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 316; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 316; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715; METAL 340; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 340; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715; METAL 345; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 376; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715; METAL 378; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715
Rhea ID
Cross Reference Brenda