| IED ID | IndEnz0002016717 |
| Enzyme Type ID | protease016717 |
| Protein Name |
Aminopeptidase T AP-T EC 3.4.11.- Heat-stable aminopeptidase |
| Gene Name | TTHA1152 |
| Organism | Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Deinococcus-Thermus Deinococci Thermales Thermaceae Thermus Thermus thermophilus Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) |
| Enzyme Sequence | MDAFKRNLEKLAELAIRVGLNLEKGQEVIATAPIEAVDFVRLLAEKAYREGASLFTVIYGDQELARKRLALAPEEGLDKAPAWLYEGMARAFREGAARLAVSGSDPKALEGLPPEKVGRAQKANARAYKPALEAITEFVTNWTIVPFAHPGWARAVFPGLPEEEAVRRLWEAIFQATRADQEDPIAAWEAHNRALHEKVAYLNARRFHALHFKGPGTDLVVGLAEGHLWQGGATATKGGRLCNPNLPTEEVFTAPHRERVEGVVRASRPLALGGTLVEGIFARFERGFAVEVRAEKGEEVLRRLLDTDEGARRLGEVALVPADNPIAKTGLVFFDTLFDENAASHIAFGQAYQENLEGRPSGEAFRKRGGNESLVHVDWMIGSEEMDVDGLYEDGTRTPLMRRGRWVV |
| Enzyme Length | 408 |
| Uniprot Accession Number | P42778 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.11.- |
| Enzyme Function | FUNCTION: Metal-dependent exopeptidase. {ECO:0000269|PubMed:16242715}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (8) |
| Keywords | 3D-structure;Aminopeptidase;Cobalt;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 2AYI; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 45,018 |
| Kinetics | |
| Metal Binding | METAL 250; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 316; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 316; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715; METAL 340; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 340; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715; METAL 345; /note=Divalent metal cation 1; /evidence=ECO:0000305|PubMed:16242715; METAL 376; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715; METAL 378; /note=Divalent metal cation 2; /evidence=ECO:0000305|PubMed:16242715 |
| Rhea ID | |
| Cross Reference Brenda |