Detail Information for IndEnz0002016721
IED ID IndEnz0002016721
Enzyme Type ID protease016721
Protein Name Archaemetzincin-1
EC 3.4.-.-
Archeobacterial metalloproteinase-like protein 1
Gene Name AMZ1 KIAA1950
Organism Homo sapiens (Human)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human)
Enzyme Sequence MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLIRTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCTEAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTLSDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQDRGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICLRKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEPGTSVSEPLTPDAGSHTFASGPEEGLSYLAASEAPLPPGGPAEAIKEHERWLAMCIQALQREVAEEDLVQVDRAVDALDRWEMFTGQLPATRQDPPSSRDSVGLRKVLGDKFSSLRRKLSARKLARAESAPRPWDGEES
Enzyme Length 498
Uniprot Accession Number Q400G9
Absorption
Active Site ACT_SITE 262; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.-.-
Enzyme Function FUNCTION: Probable zinc metalloprotease. {ECO:0000250|UniProtKB:Q8TXW1}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Alternative sequence (2); Chain (1); Compositional bias (1); Metal binding (6); Natural variant (1); Region (1)
Keywords Alternative splicing;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 54,924
Kinetics
Metal Binding METAL 261; /note=Zinc 1; via pros nitrogen; catalytic; /evidence=ECO:0000250|UniProtKB:Q8TXW1; METAL 265; /note=Zinc 1; via pros nitrogen; catalytic; /evidence=ECO:0000250|UniProtKB:Q8TXW1; METAL 272; /note=Zinc 2; /evidence=ECO:0000250|UniProtKB:Q8TXW1; METAL 277; /note=Zinc 2; /evidence=ECO:0000250|UniProtKB:Q8TXW1; METAL 296; /note=Zinc 2; /evidence=ECO:0000250|UniProtKB:Q8TXW1; METAL 299; /note=Zinc 2; /evidence=ECO:0000250|UniProtKB:Q8TXW1
Rhea ID
Cross Reference Brenda