Detail Information for IndEnz0002016743
IED ID IndEnz0002016743
Enzyme Type ID protease016743
Protein Name Archaemetzincin
EC 3.4.-.-
Gene Name amzA PF1860
Organism Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic Lineage cellular organisms Archaea Euryarchaeota Thermococci Thermococcales Thermococcaceae Pyrococcus Pyrococcus furiosus Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Enzyme Sequence MRDMIIVVPIGEVPSDVLSFLSENIESFYMKFGIGVKIIGSLPISAFSHAYDFYRNQYLARHFLPALSIIRRDYKALAVMGVTEVDLYESGLNFIFGIAHPGFGVALISLHRLYPEFYGEPPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNSIIDTDIKSWMYCKNCLRKLEERLGRGYVRGRT
Enzyme Length 192
Uniprot Accession Number Q8TZW5
Absorption
Active Site ACT_SITE 138; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_01842
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.-.-
Enzyme Function FUNCTION: Probable zinc metalloprotease whose natural substrate is unknown. {ECO:0000255|HAMAP-Rule:MF_01842}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (7)
Keywords Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 21,991
Kinetics
Metal Binding METAL 137; /note=Zinc 1; via pros nitrogen; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_01842; METAL 141; /note=Zinc 1; via pros nitrogen; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_01842; METAL 147; /note=Zinc 1; via pros nitrogen; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_01842; METAL 148; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01842; METAL 153; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01842; METAL 172; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01842; METAL 175; /note=Zinc 2; /evidence=ECO:0000255|HAMAP-Rule:MF_01842
Rhea ID
Cross Reference Brenda