| IED ID | IndEnz0002016779 |
| Enzyme Type ID | protease016779 |
| Protein Name |
Aspartic protease 6 EC 3.4.23.- |
| Gene Name | asp-6 F21F8.7 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MKTFILLAVLGLASASVHQHKIVWRESKKMGMIRTGQYPAYLEYQRNLRAVSPNVLANLPQNVNDFGDFEYLGNITIGTPDQGFIVVLDTGSSNLWIPGPTCKTNCKTKSKFDSTASSTFVKNGKSWTIQYGSGDAAGILGQDTVRFGAKGDSQLSVPTTTFGIASKISADFKNDATDGILGLAFTSLAVDGVVPPLINAINQGILDQPLFSVWLEHRGAANNVGGGVFTYGAIDTTNCGALVAYQPLSSATYYQFKAAGFKLGSYSNTKTVDVISDTGTSFLGGPQSVVDGLAKAAGATYDDFNEVYFIDCAAQPGTLDITIGTNTYSIQPVNYIVDAGNGQCLFAAFPFDFGGFGPSWILGDPFIRQYCNIYDIGNKRMGFAPSLQK |
| Enzyme Length | 389 |
| Uniprot Accession Number | O01530 |
| Absorption | |
| Active Site | ACT_SITE 89; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 277; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Aspartic protease. {ECO:0000250|UniProtKB:Q9N9H4}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Disulfide bond (2); Domain (1); Glycosylation (1); Signal peptide (1) |
| Keywords | Aspartyl protease;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17081123}. Note=Secreted into the pseudocoelom. {ECO:0000269|PubMed:17081123}. |
| Modified Residue | |
| Post Translational Modification | PTM: Glycosylated. Has phosphorylcholine-substituted oligosaccharide N-glycans. {ECO:0000269|PubMed:17081123}. |
| Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11778048; 12410314; 12679813; 14704431; 18182484; 19922876; 21110867; 21177967; 21673804; 22560298; 23800452; 25487147; 26351692; 27506200; 31216475; |
| Motif | |
| Gene Encoded By | |
| Mass | 41,520 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |