Detail Information for IndEnz0002016779
IED ID IndEnz0002016779
Enzyme Type ID protease016779
Protein Name Aspartic protease 6
EC 3.4.23.-
Gene Name asp-6 F21F8.7
Organism Caenorhabditis elegans
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans
Enzyme Sequence MKTFILLAVLGLASASVHQHKIVWRESKKMGMIRTGQYPAYLEYQRNLRAVSPNVLANLPQNVNDFGDFEYLGNITIGTPDQGFIVVLDTGSSNLWIPGPTCKTNCKTKSKFDSTASSTFVKNGKSWTIQYGSGDAAGILGQDTVRFGAKGDSQLSVPTTTFGIASKISADFKNDATDGILGLAFTSLAVDGVVPPLINAINQGILDQPLFSVWLEHRGAANNVGGGVFTYGAIDTTNCGALVAYQPLSSATYYQFKAAGFKLGSYSNTKTVDVISDTGTSFLGGPQSVVDGLAKAAGATYDDFNEVYFIDCAAQPGTLDITIGTNTYSIQPVNYIVDAGNGQCLFAAFPFDFGGFGPSWILGDPFIRQYCNIYDIGNKRMGFAPSLQK
Enzyme Length 389
Uniprot Accession Number O01530
Absorption
Active Site ACT_SITE 89; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 277; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.23.-
Enzyme Function FUNCTION: Aspartic protease. {ECO:0000250|UniProtKB:Q9N9H4}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (2); Domain (1); Glycosylation (1); Signal peptide (1)
Keywords Aspartyl protease;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17081123}. Note=Secreted into the pseudocoelom. {ECO:0000269|PubMed:17081123}.
Modified Residue
Post Translational Modification PTM: Glycosylated. Has phosphorylcholine-substituted oligosaccharide N-glycans. {ECO:0000269|PubMed:17081123}.
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11778048; 12410314; 12679813; 14704431; 18182484; 19922876; 21110867; 21177967; 21673804; 22560298; 23800452; 25487147; 26351692; 27506200; 31216475;
Motif
Gene Encoded By
Mass 41,520
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda