IED ID |
IndEnz0002016908 |
Enzyme Type ID |
protease016908 |
Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpC1
|
Gene Name |
clpC1 MSMEG_6091 MSMEI_5933 |
Organism |
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) |
Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Corynebacteriales
Mycobacteriaceae
Mycolicibacterium
Mycolicibacterium smegmatis (Mycobacterium smegmatis)
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
|
Enzyme Sequence |
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAIDLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAAALRDKEKQLVAQRAEREKQWRSGDLDVVAEVDDEQIAEVLGNWTGIPVFKLTEEETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFSQGGSENNYERMKQKVHDELKKHFRPEFLNRIDDIIVFHQLTQDEIIQMVDLMIGRVSNQLKTKDMALELSDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQLVTVDVEGWDGEGQGEDAKFTFSGGPKRAETAEPDLAGAGAAGAPTAGTE |
Enzyme Length |
848 |
Uniprot Accession Number |
A0R574 |
Absorption |
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Active Site |
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Activity Regulation |
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Binding Site |
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Calcium Binding |
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catalytic Activity |
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DNA Binding |
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EC Number |
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Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2 (Probable). {ECO:0000250, ECO:0000269|PubMed:20025669, ECO:0000305}. |
Temperature Dependency |
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PH Dependency |
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Pathway |
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nucleotide Binding |
NP_BIND 553..560; /note=ATP; /evidence=ECO:0000255; NP_BIND 617..626; /note=ATP; /evidence=ECO:0000255 |
Features |
Chain (1); Domain (2); Nucleotide binding (2); Region (3) |
Keywords |
ATP-binding;Chaperone;Nucleotide-binding;Reference proteome;Repeat |
Interact With |
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Induction |
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Subcellular Location |
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Modified Residue |
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Post Translational Modification |
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Signal Peptide |
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Structure 3D |
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Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
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Gene Encoded By |
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Mass |
93,553 |
Kinetics |
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Metal Binding |
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Rhea ID |
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Cross Reference Brenda |
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