Detail Information for IndEnz0002017021
IED ID IndEnz0002017021
Enzyme Type ID protease017021
Protein Name ATP-dependent Clp protease ATP-binding subunit ClpL
Gene Name clpL SAOUHSC_02862
Organism Staphylococcus aureus (strain NCTC 8325 / PS 47)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus Staphylococcus aureus Staphylococcus aureus (strain NCTC 8325 / PS 47)
Enzyme Sequence MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
Enzyme Length 701
Uniprot Accession Number Q2FV74
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Required for the development of induced thermotolerance and intracellular multiplication within bovine mammary epithelial cells. {ECO:0000269|PubMed:15554981}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding NP_BIND 126..133; /note=ATP; /evidence=ECO:0000255; NP_BIND 457..464; /note=ATP; /evidence=ECO:0000255
Features Chain (1); Domain (1); Nucleotide binding (2); Region (3)
Keywords ATP-binding;Chaperone;Nucleotide-binding;Reference proteome;Virulence
Interact With
Induction INDUCTION: Expression is sigma B-dependent. {ECO:0000269|PubMed:15554981}.
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 25225270;
Motif
Gene Encoded By
Mass 77,836
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda