| IED ID |
IndEnz0002017021 |
| Enzyme Type ID |
protease017021 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpL
|
| Gene Name |
clpL SAOUHSC_02862 |
| Organism |
Staphylococcus aureus (strain NCTC 8325 / PS 47) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Firmicutes
Bacilli
Bacillales
Staphylococcaceae
Staphylococcus
Staphylococcus aureus
Staphylococcus aureus (strain NCTC 8325 / PS 47)
|
| Enzyme Sequence |
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK |
| Enzyme Length |
701 |
| Uniprot Accession Number |
Q2FV74 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Required for the development of induced thermotolerance and intracellular multiplication within bovine mammary epithelial cells. {ECO:0000269|PubMed:15554981}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
NP_BIND 126..133; /note=ATP; /evidence=ECO:0000255; NP_BIND 457..464; /note=ATP; /evidence=ECO:0000255 |
| Features |
Chain (1); Domain (1); Nucleotide binding (2); Region (3) |
| Keywords |
ATP-binding;Chaperone;Nucleotide-binding;Reference proteome;Virulence |
| Interact With |
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| Induction |
INDUCTION: Expression is sigma B-dependent. {ECO:0000269|PubMed:15554981}. |
| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
25225270;
|
| Motif |
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| Gene Encoded By |
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| Mass |
77,836 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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