Detail Information for IndEnz0002017324
IED ID IndEnz0002017324
Enzyme Type ID protease017324
Protein Name ATP-dependent Clp protease ATP-binding subunit ClpX
Gene Name clpX OTT_0007
Organism Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Alphaproteobacteria Rickettsiales Rickettsiaceae Rickettsieae Orientia Orientia tsutsugamushi (Rickettsia tsutsugamushi) Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Enzyme Sequence MAKKIDNKALSCSFCCKNQNEVKKLIAGFSGFICDECIELCIHLIEEERKSNLAISNYSKLPPKKIYEAINAHVVGQQQAAKILAVAVYIQCIRFEHRELADLVAKSNVLLIGPTGCGKTLIAQTLAKIINVPFAMADATSLTEAGYVGEDVENIILRLLQAADFNVERAQKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKIMEGTIALVPPQGGRKHPQQEFIQIDTTNMLFICGGAFTGIEKIIEARTSQSTIGFEATVKSKHDQDYNQILNNLEADDLTKFGLIPEFLGRLPVIATLSDLNQQSLVDILTKPKNALVKQYQKLFELDGAELIFEEEALVAIAQKALAKKTGARGLRAILECVLLDTMFELSNLKNMQVIITADIVKNNLKPIIKPKLQKKSAKKKVTA
Enzyme Length 417
Uniprot Accession Number B3CQC6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding NP_BIND 114..121; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175
Features Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1)
Keywords ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,948
Kinetics
Metal Binding METAL 12; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 15; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 34; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 37; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250
Rhea ID
Cross Reference Brenda