| IED ID |
IndEnz0002017572 |
| Enzyme Type ID |
protease017572 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit CLPT2, chloroplastic
|
| Gene Name |
CLPT2 CLPS2 At4g12060 F16J13.130 |
| Organism |
Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Viridiplantae
Streptophyta
Streptophytina
Embryophyta
Tracheophyta
Euphyllophyta
Spermatophyta
Magnoliopsida
Mesangiospermae
eudicotyledons
Gunneridae
Pentapetalae
rosids
malvids
Brassicales
Brassicaceae
Camelineae
Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
|
| Enzyme Sequence |
MAAHSSCNFALTNPIISQIDSFSKKKLSVPLYFFSTRKALTNPWLGVVDSSLSLTSPVSALQTNRPRRIHKSAISSLPTANPDLVVSDAKKPKWSWRAIKSFAMGELEARKLKYPNTGTEALLMGILIEGTSFTSKFLRANKIMLYKVREETVKLLGKADMYFFSPEHPPLTEDAQRALDSALDQNLKAGGIGEVMPAHILLGIWSEVESPGHKILATLGFTDEKSKELESFASESGFLDE |
| Enzyme Length |
241 |
| Uniprot Accession Number |
Q8GW78 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Accessory protein regulating the assembly of the plastidial Clp protease system (PubMed:21266658, PubMed:25921872). CLPT1 first binds to the heptameric P-ring containing the CLP3-6 subunits followed by CLPT2, and only then does the P-ring combine with the R-ring composed of the clpP1 and CLPR1-4 subunits (PubMed:21266658). Once the core complex is fully assembled, it then associates to the CLPC chaperone partner to form the functional protease (PubMed:21266658). CLPT2 and CLPT1 are partially redundant (PubMed:25921872). {ECO:0000269|PubMed:21266658, ECO:0000269|PubMed:25921872}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (1); Chain (1); Domain (1); Erroneous gene model prediction (2); Helix (9); Mutagenesis (3); Region (2); Sequence conflict (3); Transit peptide (1) |
| Keywords |
3D-structure;Chloroplast;Plastid;Reference proteome;Repeat;Transit peptide |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000269|PubMed:14593120, ECO:0000269|PubMed:18431481}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
4Y0C;
|
| Mapped Pubmed ID |
12185496;
12938931;
14576160;
16207701;
16766689;
16980539;
17181860;
18633119;
18650403;
28627464;
32663165;
|
| Motif |
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| Gene Encoded By |
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| Mass |
26,561 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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