IED ID |
IndEnz0002017872 |
Enzyme Type ID |
protease017872 |
Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
|
Gene Name |
clpX HP_1374 |
Organism |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
Taxonomic Lineage |
cellular organisms
Bacteria
Proteobacteria
delta/epsilon subdivisions
Epsilonproteobacteria
Campylobacterales
Helicobacteraceae
Helicobacter
Helicobacter pylori (Campylobacter pylori)
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
|
Enzyme Sequence |
MNETLYCSFCKKPESRDPKKRRIIFASNLNKDVCVCEYCIDVMHGELHKYDNSLLALKRDRLRRMESSAYEEEFLLSYIPAPKELKAVLDNYVIGQEQAKKVFSVAVYNHYKRLSFKEKLKKQDNQDSNVELEHLEEVELSKSNILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNVQKAQKGIVFIDEIDKISRLSENRSITRDVSGEGVQQALLKIVEGSLVNIPPKGGRKHPEGNFIQIDTSDILFICAGAFDGLAEIIKKRTTQNVLGFTQEKMSKKEQEAILHLVQTHDLVTYGLIPELIGRLPVLSTLDSISLEAMVDILQKPKNALIKQYQQLFKMDEVDLIFEEEAIKEIAQLALERKTGARGLRAIIEDFCLDIMFDLPKLKGSEVRITKDCVLKQAEPLIIAKTHSKILP |
Enzyme Length |
446 |
Uniprot Accession Number |
O25926 |
Absorption |
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Active Site |
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Activity Regulation |
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Binding Site |
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Calcium Binding |
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catalytic Activity |
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DNA Binding |
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EC Number |
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Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
Temperature Dependency |
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PH Dependency |
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Pathway |
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nucleotide Binding |
NP_BIND 150..157; /note=ATP |
Features |
Beta strand (8); Chain (1); Domain (1); Helix (20); Metal binding (4); Nucleotide binding (1); Turn (4) |
Keywords |
3D-structure;ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Reference proteome;Zinc |
Interact With |
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Induction |
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Subcellular Location |
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Modified Residue |
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Post Translational Modification |
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Signal Peptide |
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Structure 3D |
X-ray crystallography (1) |
Cross Reference PDB |
1UM8;
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Mapped Pubmed ID |
11196647;
24627523;
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Motif |
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Gene Encoded By |
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Mass |
50,353 |
Kinetics |
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Metal Binding |
METAL 7; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 10; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 36; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 39; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
Rhea ID |
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Cross Reference Brenda |
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