| IED ID |
IndEnz0002017872 |
| Enzyme Type ID |
protease017872 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
|
| Gene Name |
clpX HP_1374 |
| Organism |
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Proteobacteria
delta/epsilon subdivisions
Epsilonproteobacteria
Campylobacterales
Helicobacteraceae
Helicobacter
Helicobacter pylori (Campylobacter pylori)
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
|
| Enzyme Sequence |
MNETLYCSFCKKPESRDPKKRRIIFASNLNKDVCVCEYCIDVMHGELHKYDNSLLALKRDRLRRMESSAYEEEFLLSYIPAPKELKAVLDNYVIGQEQAKKVFSVAVYNHYKRLSFKEKLKKQDNQDSNVELEHLEEVELSKSNILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNVQKAQKGIVFIDEIDKISRLSENRSITRDVSGEGVQQALLKIVEGSLVNIPPKGGRKHPEGNFIQIDTSDILFICAGAFDGLAEIIKKRTTQNVLGFTQEKMSKKEQEAILHLVQTHDLVTYGLIPELIGRLPVLSTLDSISLEAMVDILQKPKNALIKQYQQLFKMDEVDLIFEEEAIKEIAQLALERKTGARGLRAIIEDFCLDIMFDLPKLKGSEVRITKDCVLKQAEPLIIAKTHSKILP |
| Enzyme Length |
446 |
| Uniprot Accession Number |
O25926 |
| Absorption |
|
| Active Site |
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| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
NP_BIND 150..157; /note=ATP |
| Features |
Beta strand (8); Chain (1); Domain (1); Helix (20); Metal binding (4); Nucleotide binding (1); Turn (4) |
| Keywords |
3D-structure;ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Reference proteome;Zinc |
| Interact With |
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| Induction |
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| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
1UM8;
|
| Mapped Pubmed ID |
11196647;
24627523;
|
| Motif |
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| Gene Encoded By |
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| Mass |
50,353 |
| Kinetics |
|
| Metal Binding |
METAL 7; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 10; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 36; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 39; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
| Rhea ID |
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| Cross Reference Brenda |
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