IED ID |
IndEnz0002017909 |
Enzyme Type ID |
protease017909 |
Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
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Gene Name |
clpX SAV_5449 |
Organism |
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) |
Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Streptomycetales
Streptomycetaceae
Streptomyces
Streptomyces avermitilis
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
|
Enzyme Sequence |
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLEGYVVGQEAAKKALSVAVYNHYKRVQAGENGGGQSREDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNVLFIVGGAFAGLEKLIESRAGAKGIGFGATIRSKRELESKDQFEDVMPEDLVKFGMIPEFIGRLPVITSVHNLDREALLQILVEPRNALVKQYQRLFELDGVELDFEREALEAIADQAILRQTGARGLRAIMEEVLMSVMYEVPSRKDVARVVITADVVHSNVNPTLIPRDARGRGPGEQKTA |
Enzyme Length |
428 |
Uniprot Accession Number |
Q820F8 |
Absorption |
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Active Site |
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Activity Regulation |
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Binding Site |
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Calcium Binding |
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catalytic Activity |
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DNA Binding |
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EC Number |
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Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
Temperature Dependency |
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PH Dependency |
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Pathway |
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nucleotide Binding |
NP_BIND 123..130; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175 |
Features |
Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1) |
Keywords |
ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Reference proteome;Zinc |
Interact With |
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Induction |
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Subcellular Location |
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Modified Residue |
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Post Translational Modification |
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Signal Peptide |
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Structure 3D |
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Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
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Gene Encoded By |
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Mass |
46,869 |
Kinetics |
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Metal Binding |
METAL 13; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 16; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 35; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 38; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
Rhea ID |
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Cross Reference Brenda |
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