| IED ID |
IndEnz0002017923 |
| Enzyme Type ID |
protease017923 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
|
| Gene Name |
clpX SGR_4925 |
| Organism |
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Streptomycetales
Streptomycetaceae
Streptomyces
Streptomyces griseus group
Streptomyces griseus subgroup
Streptomyces griseus
Streptomyces griseus subsp. griseus
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
| Enzyme Sequence |
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLEGYVVGQEPAKKALSVAVYNHYKRVQAGENGGGAGREDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNVLFIVGGAFSGLEKIIESRAGAKGIGFGATIRSKLEIQASDQFQEVMPEDLVKFGMIPEFIGRLPVLTSVHNLDREALLQILIEPRNALVKQYQRLFELDGVELDFEREALEAIADQAILRQTGARGLRAIMEEVLQSVMYEVPSRKDVARVVITPDVVRNNVNPTLVPREPRTIGKNDGGRHEKSA |
| Enzyme Length |
432 |
| Uniprot Accession Number |
B1VXA8 |
| Absorption |
|
| Active Site |
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| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
NP_BIND 123..130; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175 |
| Features |
Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1); Region (1) |
| Keywords |
ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Zinc |
| Interact With |
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| Induction |
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| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
|
| Mass |
47,314 |
| Kinetics |
|
| Metal Binding |
METAL 13; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 16; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 35; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 38; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
| Rhea ID |
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| Cross Reference Brenda |
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