| IED ID |
IndEnz0002017994 |
| Enzyme Type ID |
protease017994 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
|
| Gene Name |
clpX LA_2558 |
| Organism |
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Spirochaetes
Spirochaetia
Leptospirales
Leptospiraceae
Leptospira
Leptospira interrogans
Leptospira interrogans serovar Lai
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
|
| Enzyme Sequence |
MAKKTPGNNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEVPSPADIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNADNDIKKAEVGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEYLQVDTKNILFILGGAFVDLPNIIKSRTGIKTIGFGSEEQRIQSENKDVLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVDMLRQIFREPKNSVLKQYTRLLELENVKLTFHDEAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVIANRVAPTLILKKESKIA |
| Enzyme Length |
420 |
| Uniprot Accession Number |
Q8F353 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
NP_BIND 122..129; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175 |
| Features |
Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1) |
| Keywords |
ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Reference proteome;Zinc |
| Interact With |
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| Induction |
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| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
|
| Mass |
46,562 |
| Kinetics |
|
| Metal Binding |
METAL 16; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 19; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 38; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 41; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
| Rhea ID |
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| Cross Reference Brenda |
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