Detail Information for IndEnz0002017994
IED ID IndEnz0002017994
Enzyme Type ID protease017994
Protein Name ATP-dependent Clp protease ATP-binding subunit ClpX
Gene Name clpX LA_2558
Organism Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic Lineage cellular organisms Bacteria Spirochaetes Spirochaetia Leptospirales Leptospiraceae Leptospira Leptospira interrogans Leptospira interrogans serovar Lai Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Enzyme Sequence MAKKTPGNNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEVPSPADIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNADNDIKKAEVGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEYLQVDTKNILFILGGAFVDLPNIIKSRTGIKTIGFGSEEQRIQSENKDVLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVDMLRQIFREPKNSVLKQYTRLLELENVKLTFHDEAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVIANRVAPTLILKKESKIA
Enzyme Length 420
Uniprot Accession Number Q8F353
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding NP_BIND 122..129; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175
Features Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1)
Keywords ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Reference proteome;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 46,562
Kinetics
Metal Binding METAL 16; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 19; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 38; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 41; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250
Rhea ID
Cross Reference Brenda