Detail Information for IndEnz0002018057
IED ID IndEnz0002018057
Enzyme Type ID protease018057
Protein Name ATP-dependent Clp protease ATP-binding subunit ClpX
Gene Name clpX Mext_2417
Organism Methylorubrum extorquens (strain PA1) (Methylobacterium extorquens)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Alphaproteobacteria Hyphomicrobiales Methylobacteriaceae Methylorubrum Methylorubrum extorquens (Methylobacterium dichloromethanicum) (Methylobacterium extorquens) Methylorubrum extorquens (strain PA1) (Methylobacterium extorquens)
Enzyme Sequence MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLERIISQRGKGTSIGFGASVQAPDDRRTGEVFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEEALKKILQEPKNALVKQYQRLFEMENVELTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVEGKSRPLFIHGDRNKEAPASVSA
Enzyme Length 423
Uniprot Accession Number A9W5F6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding NP_BIND 119..126; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175
Features Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1)
Keywords ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 46,520
Kinetics
Metal Binding METAL 15; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 18; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 37; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 40; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250
Rhea ID
Cross Reference Brenda