Detail Information for IndEnz0002018072
IED ID IndEnz0002018072
Enzyme Type ID protease018072
Protein Name ATP-dependent Clp protease ATP-binding subunit ClpX
Gene Name clpX TT_C0251
Organism Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Deinococcus-Thermus Deinococci Thermales Thermaceae Thermus Thermus thermophilus Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
Enzyme Sequence MKRPRPHCSFCGLRPPETGRLLESPIEDVYICEDCVERAQEILAQEERRAPKGPSRLPRPQEIKAHLDQYVVGQEAAKRALSVAVYNHYKRLLHPEAEIGKANILLIGPTGTGKTLLAETLARFLDVPFAIADATTLTEAGYVGEDVENVLLRLLQNADFDVERAEMGIVYIDEIDKIARKSENPSLTRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEFIPVNTKNILFILGGAFEGLENIVKARVGKTTIGFTGERREREEPLEVIPEDLIKFGMIPEFVGRAPLIVQLHPLGEDDLVRILTEPKNALVKQYQELFRMEGIELRFTQAALKEVARRALKRGTGARGLRAILEKAMVDLMFEAPGSGVKEIVFDLPHLDHPLKALEEARLRQAS
Enzyme Length 399
Uniprot Accession Number Q72L14
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding NP_BIND 109..116; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175
Features Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1)
Keywords ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 44,435
Kinetics
Metal Binding METAL 8; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 11; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 32; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 35; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250
Rhea ID
Cross Reference Brenda