| IED ID |
IndEnz0002018111 |
| Enzyme Type ID |
protease018111 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
|
| Gene Name |
clpX TW285 |
| Organism |
Tropheryma whipplei (strain TW08/27) (Whipple's bacillus) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Micrococcales
Tropherymataceae
Tropheryma
Tropheryma whipplei (Whipple's bacillus) (Tropheryma whippelii)
Tropheryma whipplei (strain TW08/27) (Whipple's bacillus)
|
| Enzyme Sequence |
MTDDTEYRCSFCGKEHHQVDDLIAGPDVRICSECVVLSCEIVEDRRNEALAKQDAFIKRKQRSVLEGLPKPAEIYAFLDEYVIGQQKAKRDLSVAVYNHYKRLVSTKSESENEVELSKSNILLIGPTGCGKTYLAQTLARMLRVPFAVADATALTEAGYVGDDVENVLLKLLQDADFDITRAEAGIVCIDEIDKISRKADSPSITRDVSGEGVQQALLKILEGTAASVPLQGGKKHTQYEQASINTRNILFIVAGAFSGIEEIISSRIGRSNMGFGSDLLRKDTDVFDQILPEDLRKFGLIPEFIGRLPIVTAISHLDGEDMIRVLTEPKNALVKQYKRLFSLDGVSLGFDHEALEAIVELALKRKTGARALRSVMESILSPIMFDVPSRGDIESVRITAETVAGGGPHLTMRCARSNYIRSA |
| Enzyme Length |
423 |
| Uniprot Accession Number |
Q83MI6 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
NP_BIND 126..133; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175 |
| Features |
Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1) |
| Keywords |
ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Zinc |
| Interact With |
|
| Induction |
|
| Subcellular Location |
|
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
46,563 |
| Kinetics |
|
| Metal Binding |
METAL 9; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 12; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 31; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 34; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
| Rhea ID |
|
| Cross Reference Brenda |
|