| IED ID |
IndEnz0002018131 |
| Enzyme Type ID |
protease018131 |
| Protein Name |
ATP-dependent Clp protease ATP-binding subunit ClpX
|
| Gene Name |
clpX MSMEG_4671 MSMEI_4553 |
| Organism |
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Actinobacteria
Actinomycetia (high G+C Gram-positive bacteria)
Corynebacteriales
Mycobacteriaceae
Mycolicibacterium
Mycolicibacterium smegmatis (Mycobacterium smegmatis)
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
|
| Enzyme Sequence |
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELADADDVKLDELPKPAEIREFLEGYVIGQDSAKRTLAVAVYNHYKRIQAGEKSRDSRSEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIVAGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFGLIPEFIGRLPVVASVTNLDKASLVKILSEPKNALVKQYVRLFEMDGVELEFTEEALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVTKETVQDNVLPTIVPRKPSRSERRDKSA |
| Enzyme Length |
426 |
| Uniprot Accession Number |
A0R196 |
| Absorption |
|
| Active Site |
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| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. {ECO:0000255|HAMAP-Rule:MF_00175}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
NP_BIND 122..129; /note=ATP; /evidence=ECO:0000255|HAMAP-Rule:MF_00175 |
| Features |
Chain (1); Domain (1); Metal binding (4); Nucleotide binding (1) |
| Keywords |
ATP-binding;Chaperone;Metal-binding;Nucleotide-binding;Reference proteome;Zinc |
| Interact With |
|
| Induction |
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| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
|
| Mass |
46,676 |
| Kinetics |
|
| Metal Binding |
METAL 13; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 16; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 35; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250; METAL 38; /note=Zinc; /evidence=ECO:0000255|PROSITE-ProRule:PRU01250 |
| Rhea ID |
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| Cross Reference Brenda |
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